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indoxam

 
National Institutes of Health

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2 relations

Broader (2)

CarbamatesIndolizines

Papers overview

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2010
2010
Production of vascular endothelial growth factors from human lung macrophages induced by group IIA and group X secreted phospholipases A2.
Angiogenesis and lymphangiogenesis mediated by vascular endothelial growth factors (VEGFs) are main features of chronic… Expand
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2009
2009
Expression of phospholipases A2 in primary human lung macrophages: role of cytosolic phospholipase A2-alpha in arachidonic acid release and platelet activating factor synthesis.
Macrophages are a major source of lipid mediators in the human lung. Expression and contribution of cytosolic (cPLA(2)) and… Expand
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2009
2009
Lung mast cells are a source of secreted phospholipases A2.
BACKGROUND Secreted phospholipases A(2) (sPLA(2)s) are released in plasma and other biologic fluids of patients with inflammatory… Expand
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Highly Cited
2005
Highly Cited
2005
Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor.
Secreted phospholipases A(2) (sPLA(2)) are enzymes released in plasma and extracellular fluids during inflammatory diseases… Expand
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2004
2004
Inhibition of the complete set of mammalian secreted phospholipases A(2) by indole analogues: a structure-guided study.
Structure-guided design was employed in a search for potent and selective inhibitors of mammalian secreted phospholipases A(2… Expand
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Highly Cited
2002
Highly Cited
2002
Interfacial kinetic and binding properties of the complete set of human and mouse groups I, II, V, X, and XII secreted phospholipases A2.
Expression of the full set of human and mouse groups I, II, V, X, and XII secreted phospholipases A(2) (sPLA(2)s) in Escherichia… Expand
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Highly Cited
2002
Highly Cited
2002
Human group IIA secretory phospholipase A2 induces neuronal cell death via apoptosis.
Expression of group IIA secretory phospholipase A2 (sPLA2-IIA) is documented in the cerebral cortex (CTX) after ischemia… Expand
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2001
2001
Group X secretory phospholipase A(2) induces potent productions of various lipid mediators in mouse peritoneal macrophages.
We have previously shown the expression of group X secretory phospholipase A(2) (sPLA(2)-X) in mouse splenic macrophages and its… Expand
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Highly Cited
2000
Highly Cited
2000
Structures, enzymatic properties, and expression of novel human and mouse secretory phospholipase A(2)s.
Mammalian secretory phospholipase A(2)s (sPLA(2)s) form a family of structurally related enzymes that are involved in a variety… Expand
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1999
1999
Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms.
Endotoxic shock is a systemic inflammatory process, involving a variety of proinflammatory mediators. Two types of secretory… Expand
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