indole-3-glycerol-phosphate lyase activity

Known as: indole synthase activity, TSA, indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity 
Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate. [EC:4.1.2.8]
National Institutes of Health

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Review
2009
Review
2009
  • Moshe Szyf
  • Annual review of pharmacology and toxicology
  • 2009
Evidence is emerging that several diseases and behavioral pathologies result from defects in gene function. The best-studied… (More)
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Highly Cited
2005
Highly Cited
2005
LSD1 is a recently identified human lysine (K)-specific histone demethylase. LSD1 is associated with HDAC1/2; CoREST, a SANT… (More)
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Highly Cited
2005
Highly Cited
2005
Nuclear-envelope proteins have been implicated in diverse and fundamental cell functions, among them transcriptional regulation… (More)
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Highly Cited
2005
Highly Cited
2005
Highly Cited
2005
UNLABELLED HDIs are potential therapeutic agents for cancer and neurological diseases because of their abilities to alter gene… (More)
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Highly Cited
2002
Highly Cited
2002
Oxidants and inflammatory mediators such as tumour necrosis factor-alpha (TNF-alpha) activate nuclear factor kappa B (NF-kappaB… (More)
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Highly Cited
2002
Highly Cited
2002
Overexpression of the human multidrug resistance gene 1 (MDR1) is a negative prognostic factor in leukemia. Despite intense… (More)
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Highly Cited
2000
Highly Cited
2000
Maize and a variety of other plant species release volatile compounds in response to herbivore attack that serve as chemical cues… (More)
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Highly Cited
2000
Highly Cited
2000
Stra13 is a transcriptional repressor related within its basic helix-loop-helix domain with the Drosophila Hairy, Enhancer of… (More)
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Highly Cited
1997
Highly Cited
1997
Histone acetylation may act to mark and maintain transcriptionally active or inactive chromosomal domains through the cell cycle… (More)
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