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improgan

 
National Institutes of Health

Papers overview

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2011
2011
&NA; The search for the mechanism of action of improgan (a nonopioid analgesic) led to the recent discovery of CC12, a compound… Expand
2010
2010
Many analgesic drugs, including μ-opioids, cannabinoids, and the novel nonopioid analgesic improgan, produce antinociception by… Expand
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2009
2009
Improgan, a cimetidine derivative which lacks activity at known histamine, opioid or cannabinoid receptors, acts by an unknown… Expand
2007
2007
UNLABELLED Improgan is a congener of the H(2) antagonist cimetidine, which produces potent antinociception. Because a) the… Expand
2007
2007
Improgan, a chemical congener of cimetidine, is a highly effective non-opioid analgesic when injected into the CNS. Despite… Expand
2004
2004
Improgan is a compound developed from histamine antagonists which shows the pre-clinical profile of a highly effective, non… Expand
2003
2003
Improgan, a chemical congener of the H(2) antagonist cimetidine, induces antinociception following intracerebroventricular (i.c.v… Expand
2002
2002
Improgan, a nonopioid antinociceptive agent, activates descending, pain-relieving mechanisms in the brain stem, but the receptor… Expand
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2001
2001
Improgan is the prototype drug from a new class of non-opioid analgesics chemically related to histamine and histamine… Expand
2000
2000
Improgan is an analog of the H(2) antagonist cimetidine that does not act on known histamine receptors, but induces highly… Expand
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