improgan
National Institutes of Health
Papers overview
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Respiratory depression is a therapy-limiting side effect of opioid analgesics, yet our understanding of the brain circuits…
Improgan, a nonopioid antinociceptive agent, activates descending, pain-relieving mechanisms in the brain stem, but the receptor…
Abstract: Burimamide, a histamine (HA) derivative with both H2‐ and H3‐blocking properties, induces antinociception when injected…
Recent studies have shown that cimetidine, burimamide and improgan (also known as SKF92374, a cimetidine congener lacking H2…