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imidapril

Known as: (S)-3-(N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl)-1-methyl-2-oxoimidazoline-4-carboxylic acid, 1-methyl-3-(2-(N-(1-ethoxycarbonyl-3-phenylpropyl)amino)propionyl)-2-oxoimidazolidine-4-carboxylic acid, 4-Imidazolidinecarboxylic acid, 3-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-1-methyl-2-oxo-, monohydrochloride, (4S-(3(R*(R*)),4R*))- 
An angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, imidapril is converted by hydrolysis in the liver into… 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (3)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsImidazolidines
Imidapril hydrochloride

Narrower (2)

TA 6366Tanatril

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Add-on blockade of (pro)renin receptor in imidapril-treated diabetic SHRsp.
To examine the involvement of (pro)renin receptor in the accelerated organ damage in streptozotocin-induced diabetic male SHRsp… 
2007
2007
ACE inhibitors to block MMP-9 activity: new functions for old inhibitors.
2006
2006
Effects of Imidapril on Left Ventricular Mass in Chronic Hemodialysis Patients
Left ventricular hypertrophy is considered to be a major cardiovascular risk factor in hemodialysis patients. Not only high blood… 
2004
2004
Imidapril improves l-NAME-exacerbated nephrosclerosis with TGF-β1 inhibition in spontaneously hypertensive rats
Objective This study was designed to investigate whether chronic angiotensin-converting enzyme (ACE) inhibition prevents… 
Highly Cited
2003
Highly Cited
2003
Increased expression of protein kinase C isoforms in heart failure due to myocardial infarction.
The activities of cardiac protein kinase C (PKC) were examined in hemodynamically assessed rats subsequent to myocardial… 
2000
2000
Protective Effects of Imidapril on He-Ne Laser-Induced Thrombosis in Cerebral Blood Vessels of Stroke-Prone Spontaneously Hypertensive Rats
Summary Inhibitors of angiotensin converting enzyme (ACE) have been developed recently for therapeutic purposes in hypertension… 
1999
1999
ANGIOTENSIN II BLUNTS, WHILE AN ANGIOTENSIN‐CONVERTING ENZYME INHIBITOR AUGMENTS, REFLEX SYMPATHETIC INHIBITION IN HUMANS*
1. The role of angiotensin (Ang)II in and the effects of angiotensin‐converting enzyme (ACE) inhibitors on the regulation of… 
1998
1998
Electrocardiographic Changes and Mortality Due to Myocardial Infarction in Rats With or Without Imidapril Treatment
Background: Various angiotensin-converting enzyme inhibitors are known to improve heart function and prolong survival in patients… 
1997
1997
Effects of angiotensin-converting enzyme inhibitor on plasma B-type natriuretic peptide levels in patients with acute myocardial infarction.
1992
1992
[Studies on angiotensin I converting enzyme (ACE) inhibitory effect of imidapril. (I). Inhibition of various tissue ACEs in vitro].
Imidapril is a newly synthesized non-sulfhydryl-containing angiotensin I converting enzyme (ACE) inhibitor. The present study… 
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