Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 236,658,243 papers from all fields of science
Search
Sign In
Create Free Account
idarubicinol
Known as:
13-dihydroidarubicin
, 4-demethoxy-14-hydroxydaunorubicin
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
3 relations
Broader (2)
Antineoplastic Agents
Daunorubicin
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Phase I Clinical Trial of Orally Administered 4-Demethoxydaunorubicin ( Idarubicin ) with Pharmacokinetic and in Vitro Drug Sensitivity Testing in Children with Refractory Leukemia 1
C. Pui
,
S. D. Graaf
,
+4 authors
S. Murphy
2006
Corpus ID: 14395820
Fifteen children with acute leukemia in relapse, refractory to conven tional therapy, were treated with idarubicin administered…
Expand
2005
2005
Cytotoxicity of anthracyclines: Correlation with cellular uptake, intracellular distribution and DNA binding
F. Gieseler
,
H. Biersack
,
T. Brieden
,
J. Manderscheid
,
V. Nüssler
Annals of Hematology
2005
Corpus ID: 1418881
SummaryIn order to interact with topoisomerase II and induce genotoxicity, anthracyclines have to cross the outer cell membrane…
Expand
2001
2001
Oralldarubicin in Maintenance Therapy ofAcute Myeloid Leukemia
M. Musso
,
F. Porretto
,
+5 authors
G. Mariani
2001
Corpus ID: 78922695
More than half of all acute myeloid leukaemia (AML) patients are over 60 years. The disease free survival (DFS) and overall…
Expand
1996
1996
Cellular pharmacology of idarubicinol in multidrug‐resistant LoVo cell lines
G. Toffoli
,
G. Corona
,
Francisco Nadal De Simone
,
M. Gigante
,
S. de Angeli
,
M. Boiocchi
International Journal of Cancer
1996
Corpus ID: 22344428
Idarubicin (IDA) is a daunorubicin (DAU) analog that is being used to treat a variety of human malignancies. The major…
Expand
Review
1996
Review
1996
Section Review Oncologic, Endocrine & Metabolic: Recent developments with novel anthracyclines for the treatment of haematological malignancies
T. Ueda
,
T. Fukushima
1996
Corpus ID: 74586591
This review discusses recent developments with novel anthracyclines for the treatment of haematological malignancies. The…
Expand
1996
1996
Interim Results of a Phase II Study with Idarubicin in Relapsed Childhood Acute Lymphoblastic Leukemia
A. Neuendank
,
R. Hartmann
,
+5 authors
G. Henze
1996
Corpus ID: 56615020
Anthracyclines are effective drugs used for induction therapy of acute lymphoblastic leukemia (ALL). Since one of their major…
Expand
1994
1994
Comparative tumoricidal activity of idarubicin and idarubicinol in combination with cyclosporin A in MDR leukemia cells: 84
M. Tolomeo
,
R. Gancitano
,
M. Musso
,
F. Porretto
,
V. Abbadessa
,
A. Cajozzo
1994
Corpus ID: 72516746
1993
1993
Action mechanism of pharmacokinetics and metabolite Idarubicinol in acute leukemia patient of a new antitumor medicine, Idarubicin.
T. Fukushima
1993
Corpus ID: 76557463