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iclaprim

Known as: 5-[(2-cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]-2,4-Pyrimidinediamine, 5-[(2RS)-2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-ylmethyl]pyrimidine-2,4-diamine 
 
National Institutes of Health

Papers overview

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2018
2018
Background Our objective in this study was to demonstrate the safety and efficacy of iclaprim compared with vancomycin for the… Expand
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Review
2017
Review
2017
Disclosures outside the scope of this work: Dr. Minei receiv grant support from Irrespet Corp. AtoxBio. Dr. Laronga rec sation… Expand
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2009
2009
OBJECTIVES Iclaprim is a novel 2,4-diaminopyrimidine that exhibits potent, rapid bactericidal activity against major Gram… Expand
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2009
2009
The in vitro activity of iclaprim, a novel diaminopyrimidine derivative, was evaluated against 5,937 recent gram-positive… Expand
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2009
2009
Iclaprim is a novel antibacterial agent that is currently in development for the treatment of complicated skin and skin structure… Expand
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2009
2009
This study evaluated the effect of human plasma on the in vitro bactericidal activity of the novel diaminopyrimidine iclaprim… Expand
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2007
2007
OBJECTIVES A validated microbiological assay was used to measure concentrations of iclaprim (AR-100) in plasma, bronchial mucosa… Expand
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Review
2007
Review
2007
Iclaprim is a novel diaminopyrimidine, and an inhibitor of dihydrofolate reductase, which has shown potent, extended-spectrum in… Expand
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2007
2007
OBJECTIVES To assess the synergistic potential of the novel diaminopyrimidine iclaprim (formerly AR-100, Ro 48-2622), a specific… Expand
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Highly Cited
2003
Highly Cited
2003
Staphylococcus aureus strain HMC3 isolated at the Hershey Medical Center, was resistant to vancomycin (VRSA) through the presence… Expand
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