hypothemycin
National Institutes of Health
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The discovery of 20 unconventional kinetochore proteins in Trypanosoma brucei has opened a new and interesting area of…
In this study, we describe the evaluation of a cell-based protein stability assay using β-galactosidase fragment complementation…
2015 The mitogen activated protein kinase kinase kinase transforming growth factorβ-activated kinase 1 (TAK1) has emerged as an…
Many metabolites produced by various microorganisms
have proven their usefulness in the area concerning human health. However…
The impact of crystalline forces on the solid-state circular dichroism (CD) spectrum of hypothemycin (), a biologically active…
Author(s): Nishino, Mari | Advisor(s): McKerrow, James | Abstract: A search for effective treatment of African sleeping sickness…
The resorcylic acid lactone hypothemycin has been shown to inactivate protein kinases by binding to a cysteine conserved in 46…
This subset of the kinome accounts for less than 10% of all identified kinases but includes several targets implicated in…