hyperforin dicyclohexylammonium

Known as: DCHA-HF cpd, hyperforin dicyclohexylammonium salt 
 
National Institutes of Health

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Terpenes

Papers overview

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2011
2011
Induction of apoptosis in K562 cells by dicyclohexylammonium salt of hyperforin through a mitochondrial-related pathway.
Hyperforin is an abundant phloroglucinol-type constituent isolated from the extract of the flowering upper portion of the plant… (More)
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2011
2011
Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E2 Synthase-1 and Suppresses Prostaglandin E2 Formation in vivo
The acylphloroglucinol hyperforin (Hyp) from St. John's wort possesses anti-inflammatory and anti-carcinogenic properties which… (More)
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2011
2011
Hyperforin Inhibits Akt1 Kinase Activity and Promotes Caspase-Mediated Apoptosis Involving Bad and Noxa Activation in Human Myeloid Tumor Cells
BACKGROUND The natural phloroglucinol hyperforin HF displays anti-inflammatory and anti-tumoral properties of potential… (More)
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2010
2010
Hyperforin induces Ca(2+)-independent arachidonic acid release in human platelets by facilitating cytosolic phospholipase A(2) activation through select phospholipid interactions.
Here, we investigated the modulation of cytosolic phospholipase A(2) (cPLA(2))-mediated arachidonic acid (AA) release by the… (More)
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Review
2009
Review
2009
St. John's wort components and the brain: uptake, concentrations reached and the mechanisms underlying pharmacological effects.
Hypericum perforatum L. (St. John's wort) extracts have gained popularity as an alternative to conventional antidepressant drugs… (More)
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2009
2009
Mechanisms of Hyperforin as an anti-angiogenic angioprevention agent.
Hyperforin, the major lipophilic compound contained in extracts of Hypericum perforatum, is responsible for the antidepressant… (More)
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2007
2007
Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L.
Three preparations of Hypericum perforatum L. (a hydroalcoholic extract, a lipophilic extract and an ethylacetic fraction) and… (More)
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2005
2005
Potential antidepressant properties of IDN 5491 (hyperforin-trimethoxybenzoate), a semisynthetic ester of hyperforin
Hyperforin is one of the possible active principles mediating the antidepressant activity of Hypericum perforatum L. extracts… (More)
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2002
2002
Role of hyperforin in the antidepressant-like activity of Hypericum perforatum extracts
Abstract Rationale. Hyperforin has been identified as an active constituent of Hypericum perforatum but its importance in the… (More)
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Highly Cited
1984
Highly Cited
1984
Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils.
Exogenous eicosapentaenoic acid (EPA) and docosahexaenoic acid (DCHA) have been compared with exogenous arachidonic acid for… (More)
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