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hydroxyfasudil

National Institutes of Health

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analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Long-term inhibition of Rho-kinase restores the LTP impaired in chronic forebrain ischemia rats by regulating GABAA and GABAB receptors
2012
2012
Evidence of a direct cellular protective effect of Rho-kinase inhibitors on endothelin-induced cardiac myocyte hypertrophy.
2011
2011
Fasudil protects cultured N1E-115 cells against lysophosphatidic acid-induced neurite retraction through inhibition of Rho-kinase
2010
2010
Effects of sex and estrogen on chicken ductus arteriosus reactivity.
Sex hormones have an important influence on cardiovascular physiology and pathophysiology and sex differences in vascular… 
2009
2009
Effect of the rho‐kinase inhibitor hydroxyfasudil on bladder overactivity: An experimental rat model
Objectives:  To investigate the effects of the rho‐kinase inhibitor hydroxyfasudil on bladder overactivity in cyclophosphamide… 
2007
2007
Wide therapeutic time window for fasudil neuroprotection against ischemia-induced delayed neuronal death in gerbils
Review
2006
Review
2006
Rho-kinase: a potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction.
See related article, pages 299–306 Although elevated serum cholesterol levels and hypertension are independent risk factors for… 
2005
2005
Effects of Hydroxyfasudil Administered to the Nucleus Tractus Solitarii on Blood Pressure and Heart Rate in Spontaneously Hypertensive Rats
Previously, we reported that the inhibition of Rho-kinase by a microinjection of Y-27632 or the transfection of dominant-negative… 
Highly Cited
2003
Highly Cited
2003
Evidence for Protein Kinase C-Mediated Activation of Rho- Kinase in a Porcine Model of Coronary Artery Spasm
Objective—We have recently demonstrated that protein kinase C (PKC) and Rho-kinase play important roles in coronary vasospasm in… 
2001
2001
Antianginal effects of hydroxyfasudil, a Rho‐kinase inhibitor, in a canine model of effort angina
The effects of Rho‐kinase inhibitor, fasudil, and of a more specific Rho‐kinase inhibitor, hydroxyfasudil, on pacing‐induced… 
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