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hydroxybupropion

Known as: 4-hydroxy bupropion 
National Institutes of Health

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6 relations

Broader (1)

Bupropion
Hydroxybupropion:MCnc:Pt:Bld:QnHydroxybupropion:MCnc:Pt:Body fld:QnHydroxybupropion:MCnc:Pt:Ser/Plas:QnHydroxybupropion:SCnc:Pt:Ser/Plas:Qn

Papers overview

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2014
2014
Characterization of CYP 2 B 6 in a CYP 2 B 6-Humanized Mouse Model : Inducibility in the Liver by Phenobarbital and Dexamethasone and Role in Nicotine Metabolism In Vivo s
The aim of this study was to further characterize the expression and function of human CYP2B6 in a recently generated CYP2A13… 
2014
2014
Gene Variants in CYP 2 C 19 Are Associated with Altered In Vivo Bupropion Pharmacokinetics but Not Bupropion-Assisted Smoking Cessation Outcomes s
Bupropion is used clinically to treat depression and to promote smoking cessation. It is metabolized by CYP2B6 to its… 
2012
2012
Effect of Repeated Doses of Teriflunomide on a Single Oral Dose of Bupropion in Healthy Male Subjects (P04.143)
Objective: To assess the effect of repeated doses of teriflunomide on the pharmacokinetics (PK) of bupropion, a probe substrate… 
2012
2012
Liquid Chromatography Tandem mass spectrometry method for Quantification of Buproprion and Hydroxy Buproprion in Human Plasma and its application to Bioequivalence Study
A rapid, specific and robust assay based on solid phase extraction and liquid chromatography-electronspray ionization tandem mass… 
2007
2007
A Genetic Predictor of Medication Effectiveness in Smoking Cessation
Bupropion, an FDA-approved adjunctive medication for smoking cessation, is metabolized by cytochrome (CYP) P450 2B6 to… 
2007
2007
Invloed van nierfalen op de farmacokinetiek van bupropion en zijn metabolieten
Bupropion – een hulpmiddel bij stoppen met roken en tevens antidepressivum (voor het laatste is het niet in Nederland… 
2006
2006
An Evaluation of the Cytochrome P 450 Inhibition Potential of Lisdexamfetamine in Human Liver Microsomes
The human cytochrome P450 (P450) system is implicated in many drug interactions. Lisdexamfetamine dimesylate (NRP104), the… 
2005
2005
THE NATURALLY OCCURRING CYTOCHROME P 450 ( P 450 ) 2 B 6 K 262 R MUTANT OF P 450 2 B 6 EXHIBITS ALTERATIONS IN SUBSTRATE METABOLISM AND INACTIVATION
The polymorphic human cytochrome P450 (P450) 2B6 is primarily responsible for the metabolism of several clinically relevant drugs… 
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