hydroxybupropion

Known as: 4-hydroxy bupropion 
 

Topic mentions per year

Topic mentions per year

1988-2017
0519882017

Papers overview

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2012
2012
Bupropion is indicated to promote smoking cessation. Animal studies suggest that the pharmacologic activity of bupropion can be… (More)
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2009
2009
This investigation includes an evaluation of the percutaneous absorption of bupropion (BUP) and hydroxybupropion (BUPOH) in vitro… (More)
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2007
2007
A sensitive, stereoselective assay using solid phase extraction and LC-MS-MS was developed and validated for the analysis of (R… (More)
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2007
2007
A sensitive and stereoselective assay has been developed for the quantitation of the enantiomers of hydroxybupropion, an active… (More)
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2006
2006
Naltrexone (NTX) is a potent opioid antagonist used in the treatment of alcohol dependence and heroin abuse. Compared with… (More)
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2006
2006
AIM The aim of this study was to investigate the activity of the drug-metabolizing enzyme cytochrome P450 (CYP) 2B6 before and… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Our objective was to study the effect of the antiplatelet agents clopidogrel and ticlopidine on bupropion (INN… (More)
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Highly Cited
2004
Highly Cited
2004
Bupropion is an atypical antidepressant that also has usefulness as a smoking-cessation aid. Because hydroxybupropion, a major… (More)
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Highly Cited
2003
Highly Cited
2003
Bupropion is applied in depression and smoking cessation. Genetic polymorphisms in cytochrome P450 2B6 (CYP2B6) may cause… (More)
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Highly Cited
2000
Highly Cited
2000
The in vitro biotransformation of bupropion to hydroxybupropion was studied in human liver microsomes and microsomes containing… (More)
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