Skip to search formSkip to main contentSkip to account menu

hydroxybupropion

Known as: 4-hydroxy bupropion 
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

Bupropion
Hydroxybupropion:MCnc:Pt:Bld:QnHydroxybupropion:MCnc:Pt:Body fld:QnHydroxybupropion:MCnc:Pt:Ser/Plas:QnHydroxybupropion:SCnc:Pt:Ser/Plas:Qn

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Effects of Genetic Polymorphisms of CYP2B6 on the Pharmacokinetics of Bupropion and Hydroxybupropion in Healthy Chinese Subjects
Background Bupropion (BUP) is an antidepressant and its pharmacological activity is mediated by its major metabolite… 
2017
2017
Design of experiment assisted concurrent enantioseparation of bupropion and hydroxybupropion by high-performance thin-layer chromatography.
A simple and efficient high-performance thin-layer chromatographic method was developed for chiral separation of rac-bupropion… 
2016
2016
Bupropion therapy during pregnancy: the drug and its major metabolites in umbilical cord plasma and amniotic fluid.
2015
2015
Effect of CYP2B6*6 on Steady-State Serum Concentrations of Bupropion and Hydroxybupropion in Psychiatric Patients: A Study Based on Therapeutic Drug Monitoring Data
Background: The clinical effect of bupropion is mediated by its active metabolite hydroxybupropion. Previous studies have… 
2012
2012
Bupropion Hydroxylation as a Selective Marker of Rat CYP2B1 Catalytic Activity
Benzyloxyresorufin-O-dealkylation (BROD) is usually used as a marker of cytochrome P450 (P450) 2B1 in rat. However, some reports… 
2010
2010
Use of Enantiomeric Bupropion and Hydroxybupropion to Assess CYP2B6 Activity in Glomerular Kidney Diseases
Chronic kidney disease affects more than 50 million people in the U.S.1. The top three etiologies for end-stage kidney disease… 
2010
2010
The in vitro metabolism of bupropion revisited: concentration dependent involvement of cytochrome P450 2C19
The involvement of cytochrome P450 2B6 (CYP2B6) to the in vitro and in vivo metabolism of bupropion has been well studied. In… 
2007
2007
Stereoselective analysis of hydroxybupropion and application to drug interaction studies.
A sensitive and stereoselective assay has been developed for the quantitation of the enantiomers of hydroxybupropion, an active… 
2006
2006
Synthesis and hydrolytic behavior of two novel tripartate codrugs of naltrexone and 6beta-naltrexol with hydroxybupropion as potential alcohol abuse and smoking cessation agents.
1992
1992
Bupropion and alcohol fatal intoxication: case report.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)