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hydroxybupropion

Known as: 4-hydroxy bupropion 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Bupropion is indicated to promote smoking cessation. Animal studies suggest that the pharmacologic activity of bupropion can be… Expand
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2011
2011
A specific and highly sensitive liquid chromatography-electrospray mass spectrometry (LC-ESI-MS) method for the direct… Expand
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2010
2010
To create potentially superior aids to smoking cessation and/or antidepressants and to elucidate bupropion's possible mechanisms… Expand
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2008
2008
OBJECTIVE To characterize the effect of efavirenz on bupropion hydroxylation as a marker of cytochrome P450 (CYP) 2B6 activity in… Expand
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2007
2007
A sensitive, stereoselective assay using solid phase extraction and LC-MS-MS was developed and validated for the analysis of (R… Expand
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2006
2006
Naltrexone (NTX) is a potent opioid antagonist used in the treatment of alcohol dependence and heroin abuse. Compared with… Expand
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE Our objective was to study the effect of the antiplatelet agents clopidogrel and ticlopidine on bupropion (INN… Expand
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Highly Cited
2004
Highly Cited
2004
Bupropion is an atypical antidepressant that also has usefulness as a smoking-cessation aid. Because hydroxybupropion, a major… Expand
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Highly Cited
2003
Highly Cited
2003
Bupropion is applied in depression and smoking cessation. Genetic polymorphisms in cytochrome P450 2B6 (CYP2B6) may cause… Expand
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Highly Cited
2000
Highly Cited
2000
The in vitro biotransformation of bupropion to hydroxybupropion was studied in human liver microsomes and microsomes containing… Expand
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