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hydrocotarnine

Known as: 1,3-dioxolo(4,5-g)isoquinoline, 5,6,7,8-tetrahydro-4-methoxy-6-methyl- 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Tetrahydroisoquinolines

Narrower (2)

hydrocotarnine hydrobromidehydrocotarnine hydrochloride

Papers overview

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2019
2019
DITMD‐induced mitotic defects and apoptosis in tumor cells by blocking the polo‐box domain‐dependent functions of polo‐like kinase 1
2018
2018
Src-family kinase-Cbl axis negatively regulates NLRP3 inflammasome activation
Activation of the NLRP3 inflammasome is crucial for immune defense, but improper and excessive activation causes inflammatory… 
2012
2012
[Retrospective study on intravenous compound injection of cancer pain patients with oxycodone and hydrocotarnine preparation in comparison with subcutaneous administration].
In Japan, although oral oxycodone is widely used for cancer pain treatment, there is no injection preparation of oxycodone used… 
Review
2011
Review
2011
[Solutions for the clinical problems of analgesics for cancer pain treatment in Japan].
The pain experienced by cancer patients can be managed in 70-90% of cases by the World Health Organisation protocol for cancer… 
Review
2010
Review
2010
[Efficacy and safety of compound oxycodone injection for cancer pain relief-a multicenter survey of prescriptions].
Oral oxycodone has been available since 2003 in Japan. Oxycodone consumption is increasing along with the decrease in morphine… 
2009
2009
[Efficacy and safety of continuous subcutaneous injection of the compound oxycodone in cancer pain management: the first 4-year audit].
The compound oxycodone injection, but not pure oxycodone, has been available since the 1920's in Japan. The compound, containing… 
Review
2007
Review
2007
[Conversion ratio between intravenous oxycodone/hydrocotarnine and sustained-release oral oxycodone in patients with cancer pain].
The demand for oxycodone increases in the treatment of patients with cancer pain, but there is no injection formulation… 
2005
2005
Determination of Oxycodone and Hydrocotarnine in Cancer Patient Serum by High-Performance Liquid Chromatography with Electrochemical Detection
We developed an HPLC procedure using electrochemical detection for the quantitation of oxycodone and hydrocotarnine in cancer… 
1979
1979
[Biotransformation and Stability of Hydrocotarnine and Diazocarbonylhydrocotarnine and -hydrohydrastinine derivatives (author's transl)].
After oral application of the weakly basic (pKs = 6.18-6.26) and relatively stable (1 at pH = 7.4; t1/2(35 degrees C) = 6.9 h… 
1959
1959
The relation between drug-induced excitation in the cat and addiction liability.
The production of central excitation in the cat by various opium alkaloids, some synthetic analgesics, and related compounds has… 
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