homocysteine metabolic process

Known as: Hcy metabolic process, Hcy metabolism, homocysteine metabolism 
The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important… (More)
National Institutes of Health

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negative regulation of homocysteine metabolic processregulation of homocysteine metabolic process

Papers overview

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Review
2003
Review
2003
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders
Folate is a cofactor in one-carbon metabolism, during which it promotes the remethylation of homocysteine -- a cytotoxic sulfur… (More)
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Review
2003
Review
2003
Update on cobalamin, folate, and homocysteine.
Three topics affecting cobalamin, folate, and homocysteine that have generated interest, activity, and advances in recent years… (More)
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Review
2002
Review
2002
Homocysteine determinants and the evidence to what extent homocysteine determines the risk of coronary heart disease.
Cardiovascular diseases (CVD), especially coronary heart disease (CHD), are the most important causes of death in industrialized… (More)
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Review
2000
Review
2000
Pathways and regulation of homocysteine metabolism in mammals.
Two intersecting pathways, the methionine cycle and the transsulfuration sequence, compose the mechanisms for homocysteine… (More)
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Highly Cited
2000
Highly Cited
2000
The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes.
Homocysteine is a key junction metabolite in methionine metabolism. It suffers two major metabolic fates: transmethylation… (More)
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Review
1999
Review
1999
Homocysteine metabolism.
Homocysteine is a sulfur amino acid whose metabolism stands at the intersection of two pathways: remethylation to methionine… (More)
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Review
1997
Review
1997
Homocysteine and thrombotic disease.
amino acid whose metabolism is at the intersection of The more severe cases of hyperhomocysteinemia are two metabolic pathways… (More)
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Highly Cited
1996
Highly Cited
1996
Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.
BACKGROUND Methylenetetrahydrofolate reductase (MTHFR) synthesizes 5-methyltetrahydrofolate, the major carbon donor in… (More)
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Highly Cited
1995
Highly Cited
1995
Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis.
BACKGROUND Epidemiologic studies have identified hyperhomocysteinemia as a possible risk factor for atherosclerosis. We… (More)
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Highly Cited
1993
Highly Cited
1993
Vitamin status and intake as primary determinants of homocysteinemia in an elderly population.
OBJECTIVE To describe the distribution of plasma homocysteine concentrations in an elderly population and to analyze the… (More)
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