Skip to search formSkip to main contentSkip to account menu

homocysteine biosynthetic process

Known as: homocysteine anabolism, homocysteine biosynthesis, homocysteine formation 
The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid. [CHEBI:17230, GOC:ecd, GOC:mah]
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Metabonomic study of aristolochic acid-induced nephrotoxicity in rats.
This paper describes a metabonomic study characterizing the nephrotoxicity induced by aristolochic acid (AA), a suspected kidney… 
2005
2005
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
The effects of folate status and the methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism on the kinetics of… 
Review
2004
Review
2004
Homocysteine and levodopa
Epidemiologic evidence has linked elevation of serum homocysteine to an increased risk of coronary artery disease, stroke, and… 
2000
2000
Mechanisms for the formation of protein-bound homocysteine in human plasma.
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Greater than 70% of homocysteine in circulation is… 
Highly Cited
1999
Highly Cited
1999
Homocysteine, a risk factor for cardiovascular disease
Fasting hyperhomocysteinemia is an independent risk factor for coronary artery disease, stroke, peripheral vascular… 
1984
1984
O-Acetylhomoserine sulfhydrylase of the fission yeast Schizosaccharomyces pombe: partial purification, characterization, and its probable role in homocysteine biosynthesis.
A crude extract of Schizosaccharomyces pombe cells catalyzed sulfhydrylation of both O-acetyl-L-serine and O-acetyl-L-homoserine… 
Highly Cited
1978
Highly Cited
1978
Homocysteine biosynthesis in green plants. Physiological importance of the transsulfuration pathway in Chlorella sorokiniana growing under steady state conditions with limiting sulfate.
The physiological roles of the transsulfuration and direct sulfhydration pathways in Chlorella sorokiniana growing under steady… 
1975
1975
Enzymatic lesions in methionine mutants of Aspergillus nidulans: role and regulation of an alternative pathway for cysteine and methionine synthesis
In Aspergillus nidulans the pathway involving cystathionine formation is the main one for homocysteine synthesis. Mutants lacking… 
Review
1968
Review
1968
Some aspects of amino acid biosynthesis in microorganisms.
GLUTAMINE BIOSyNTHESIS 80 E. coli.. . .. 80 Other microorganisms… 
Highly Cited
1967
Highly Cited
1967
Acyl derivatives of homoserine as substrates for homocysteine synthesis in Neurospora crassa, yeast, and Escherichia coli.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)