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histone methyltransferase activity

Known as: histone methylase activity 
Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

histone methylation

Narrower (1)

histone-arginine N-methyltransferase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
[Effects of Histone Methyltransferase Inhibitors on the Survival, Apoptosis and Cell Cycle of Raji Cells].
Objective To determine the effects of three histone methylase inhibitors UNC1999, DZNep and GSK343 on the survival, apoptosis and… 
Review
2017
Review
2017
Targeting PRC2: RNA offers new opportunities
The histone methyltransferase Polycomb repressive complex 2 (PRC2) is essential for embryonic development and is dysregulated in… 
2016
2016
NKTL. When investigating coimmunoprecipitates, they observed an association of both proteins. Pharmacologic inhibition of the JAK/STAT5 signaling pathway led to an increased H3K27 trimethylation…
  • 2016
  • Corpus ID: 207760052
coimmunoprecipitates, they observed an association of both proteins. Pharmacologic inhibition of the JAK/STAT5 signaling pathway… 
2014
2014
DNA polymerase &agr; interacts with PrSet7 and mediates H4K20 monomethylation in Drosophila
ABSTRACT In human cells, appropriate monomethylation of histone H4 lysine 20 by PrSet7 (also known as SET8 and SETD7) is… 
2013
2013
The Histone Methyltransferase SUV39H1 Suppresses Embryonal Rhabdomyosarcoma Formation in Zebrafish
Epigenetics, or the reversible and heritable marks of gene regulation not including DNA sequence, encompasses chromatin… 
2011
2011
Expression Transcription 1 ( STAT 1 )-activated Gene Signal Transducer and Activator of 1-like ( DOT 1 L ) Interaction Is Required for A Novel Disrupter of Telomere Silencing Gene Regulation :
2008
2008
ING2 recruits histone methyltransferase activity with methylation site specificity distinct from histone H3 lysines 4 and 9.
2007
2007
The histone methyltransferase activity of WHISTLE is important for the induction of apoptosis and HDAC1-mediated transcriptional repression.
1982
1982
The Relationship of Myelin Basic Protein (Arginine) Methyltransferase to Myelination in Mouse Spinal Cord
Abstract: The relationship between the activity of myelin basic protein (arginine) methyltransferase and myelination in the mouse… 
1974
1974
Changes in histone methylase activity of rat brain and liver with ageing
No function has been found for the methylation of the ɛ-N-amino group of lysine in certain histones that have been demonstrated… 
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