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hirsuteine

National Institutes of Health

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Alkaloids

Papers overview

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2018
2018
Yokukansan contains compounds that antagonize the 5-HT3 receptor.
2015
2015
An efficient and target-oriented sample enrichment method for preparative separation of minor alkaloids by pH-zone-refining counter-current chromatography.
2015
2015
Chemical profiling with HPLC-FTMS of exogenous and endogenous chemicals susceptible to the administration of chotosan in an animal model of type 2 diabetes-induced dementia.
Highly Cited
2011
Highly Cited
2011
Yokukansan, a kampo medicine, protects against glutamate cytotoxicity due to oxidative stress in PC12 cells.
Highly Cited
2011
Highly Cited
2011
The Blood–Brain Barrier Permeability of Geissoschizine Methyl Ether in Uncaria Hook, a Galenical Constituent of the Traditional Japanese Medicine Yokukansan
Geissoschizine methyl ether (GM) in Uncaria hook, a galenical constituent of yokukansan is thought to be one of active components… 
Highly Cited
2011
Highly Cited
2011
Isoliquiritigenin is a Novel NMDA Receptor Antagonist in Kampo Medicine Yokukansan
Effects of a traditional Japanese medicine, yokukansan, which is composed of seven medicinal herbs, on glutamate-induced cell… 
2006
2006
Metabolites of hirsuteine and hirsutine, the major indole alkaloids of Uncaria rhynchophylla, in rats.
The metabolic fate of hirsuteine (HT) and hirsutine (HS), the major indole alkaloids of Uncaria rhynchophylla, was investigated… 
Highly Cited
1999
Highly Cited
1999
Evaluation of the Protective Effects of Alkaloids Isolated from the Hooks and Stems of Uncaria sinensis on Glutamate‐induced Neuronal Death in Cultured Cerebellar Granule Cells from Rats
We have previously shown that an aqueous extract of the hooks and stems of Uncaria sinensis (Oliv.) Havil., Uncariae Uncus Cum… 
1990
1990
[Vasodilative effects of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq. and Amsonia elliptica Roem. et Schult].
  • Y. Ozaki
  • Nihon yakurigaku zasshi. Folia pharmacologica…
  • 1990
  • Corpus ID: 36135729
Vasodilative effects of hirsutine (HS) and hirsuteine (HST) which were isolated from the domestic plant Uncaria rhynchophylla Miq… 
1989
1989
[Pharmacological studies of indole alkaloids obtained from domestic plants, Uncaria rhynchophylla Miq. and Amsonia elliptica Roem. et Schult].
  • Y. Ozaki
  • Nihon yakurigaku zasshi. Folia pharmacologica…
  • 1989
  • Corpus ID: 1651959
Pharmacological studies on hirsutine (HS), hirsuteine (HST), rhynchophylline (RP), isorhynchophylline (IRP) and… 
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