FAQ

hindbrain development

Known as: rhombencephalon development 
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
051019822018

Related topics

Related topics

4 relations

Broader (1)

brain development

Narrower (3)

hindbrain morphogenesismetencephalon developmentrhombomere development

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
hindbrain development
brain development
hindbrain morphogenesis
metencephalon development
rhombomere development

Papers overview

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Highly Cited
2007
Highly Cited
2007
Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development.
Retinoic acid (RA) is essential for normal vertebrate development, including the patterning of the central nervous system. During… (More)
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Highly Cited
2002
Highly Cited
2002
Eliminating zebrafish pbx proteins reveals a hindbrain ground state.
The vertebrate hindbrain is divided into serially homologous segments, the rhombomeres (r). Pbx and Hox proteins are hypothesized… (More)
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Highly Cited
2002
Highly Cited
2002
FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain.
The segmentation of the vertebrate hindbrain into rhombomeres is highly conserved, but how early hindbrain patterning is… (More)
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Highly Cited
2001
Highly Cited
2001
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development.
beta-Catenin is a central component of both the cadherin-catenin cell adhesion complex and the Wnt signaling pathway. We have… (More)
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Highly Cited
1999
Highly Cited
1999
Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development.
The analysis of mice mutant for both Hoxa1 and Hoxb1 suggests that these two genes function together to pattern the hindbrain… (More)
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Highly Cited
1997
Highly Cited
1997
Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function.
Analysis of mouse embryos homozygous for a loss-of-function allele of Gbx2 demonstrates that this homeobox gene is required for… (More)
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Highly Cited
1996
Highly Cited
1996
Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development.
A secreted signalling molecule encoded by the Wnt-1 gene is required for development of the central nervous system. In mouse… (More)
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Highly Cited
1993
Highly Cited
1993
Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development.
To begin to examine the function of genes that control early development in the hindbrain, we have screened an embryonic… (More)
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Highly Cited
1993
Highly Cited
1993
Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.
Krox20 is a zinc finger gene expressed in rhombomeres 3 and 5 during hindbrain development in vertebrates. Mice homozygous for a… (More)
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Highly Cited
1993
Highly Cited
1993
Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain.
The zinc finger gene Krox-20 is transcribed in two alternate segments (rhombomeres) of the developing hindbrain. To investigate… (More)
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