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heterocycle biosynthetic process

Known as: heterocycle synthesis, heterocycle biosynthesis, heterocycle formation 
The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two… 
National Institutes of Health

Papers overview

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2016
2016
Probing the reactivity of pentaphenylborole with N-H, O-H, P-H, and S-H bonds.
The reactions of molecules containing E-H functionalities (E = Group 15 or 16 element) and pentaphenylborole were investigated… 
2016
2016
Selenium-Containing Fused Bicyclic Heterocycle Diselenolodiselenole: Field Effect Transistor Study and Structure-Property Relationship.
The first application of the diselenolodiselenole (C4Se4) heterocycle as an active organic field effect transistor materials is… 
Highly Cited
2013
Highly Cited
2013
Proton Donor Acidity Controls Selectivity in Nonaromatic Nitrogen Heterocycle Synthesis
Acid-Derived Diversity Compounds with nitrogen-bearing rings have proven rather promising in pharmaceutical research, spurring… 
2011
2011
Development of a flexible strategy towards FR900482 and the mitomycins.
FR900482 and the mitomycins are two intriguing classes of alkaloid natural products that have analogous biological mechanisms and… 
2010
2010
Synthesis and structure of azole-fused indeno[2,1-c]quinolines and their anti-mycobacterial properties.
Prompted by our discovery of a new class of conformationally-locked indeno[2,1-c]quinolines as anti-mycobacterials, compounds 2a… 
2009
2009
Synthesis and biological evaluation of 1,2,4-trisubstituted imidazoles and 1,3,5-trisubstituted pyrazoles as inhibitors of transforming growth factor beta type 1 receptor (ALK5).
2005
2005
Excision of the epothilone synthetase B cyclization domain and demonstration of in trans condensation/cyclodehydration activity.
The epothilones are potent anticancer natural products produced by a polyketide synthase (PKS)-nonribosomal peptide synthetase… 
2002
2002
The thermal decomposition of thiirane: a mechanistic study by ab initio MO theory.
Using high-level ab initio MO methods, we have identified two reaction pathways with different thermodynamic and kinetic… 
2001
2001
Radical cyclization in heterocycle synthesis. 12. Sulfanyl radical addition-addition-cyclization (SRAAC) of unbranched diynes and its application to the synthesis of A-ring fragment of 1alpha,25…
Sulfanyl radical addition-addition-cyclization (SRAAC) of unbranched diynes proceeded smoothly to give cyclized exo-olefins… 
2000
2000
Use of pK(a) differences to enhance the formation of base triplets involving C-G and G-C base pairs.
Two C-nucleosides are employed for the recognition of dC-dG base pairs. Both derivatives are related to dC but lack the O2… 
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