heparin biosynthetic process

Known as: heparin formation, heparin biosynthesis, heparin synthesis 
The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000… (More)

Topic mentions per year

Topic mentions per year

1950-2017
01219502016

Papers overview

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2012
2012
Heparin is the most widely used pharmaceutical to control blood coagulation in modern medicine. A health crisis that took place… (More)
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2011
2011
Deficiency of the heparan sulfate biosynthesis enzyme N-deacetylase/N-sulfotransferase 1 (NDST1) in mice causes severely… (More)
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2006
2006
Biosynthesis of heparin, a mast cell-derived glycosaminoglycan with widespread importance in medicine, has not been fully… (More)
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2002
2002
The content and synthesis of heparin and mast cell-dependent skin oedema (as an indirect evaluation of histamine and serotonin… (More)
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2001
2001
We have previously generated a mouse strain with a defect in its heparin biosynthesis by targeting the gene for N-deacetylase/N… (More)
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2001
2001
The tumor suppressors EXT1 and EXT2 are associated with hereditary multiple exostoses and encode bifunctional… (More)
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1994
1994
A 110-kDa protein involved in heparin biosynthesis in mouse mastocytoma cells was previously shown to express both glucosaminyl N… (More)
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1992
1992
The last step of heparin biosynthesis is thought to involve the action of 3-O-sulfotransferase resulting in the formation of an… (More)
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1981
1981
Heparin biosynthesis has been investigated with mouse mastocytoma in vitro. Minced tumour tissue catalysed the incorporation of… (More)
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