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heparin biosynthetic process

Known as: heparin formation, heparin biosynthesis, heparin synthesis 
The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Heparosan-coated liposomes for drug delivery
Liposomal encapsulation is a useful drug delivery strategy for small molecules, especially chemotherapeutic agents such as… 
Review
2015
Review
2015
Can We Produce Heparin/Heparan Sulfate Biomimetics Using “Mother-Nature” as the Gold Standard?
Heparan sulfate (HS) and heparin are glycosaminoglycans (GAGs) that are heterogeneous in nature, not only due to differing… 
2011
2011
Controlled Photochemical Depolymerization of K5 Heparosan, a Bioengineered Heparin Precursor.
2006
2006
Heparan sulfate C5-epimerase is essential for heparin biosynthesis in mast cells
Biosynthesis of heparin, a mast cell–derived glycosaminoglycan with widespread importance in medicine, has not been fully… 
1997
1997
Mouse Mastocytoma Cells Synthesize Undersulfated Heparin and Chondroitin Sulfate in the Presence of Brefeldin A*
In order to study the subcellular localization and organization of the enzymes involved in the glycosylation of the hybrid… 
Highly Cited
1986
Highly Cited
1986
Histamine and chondroitin sulfate E proteoglycan released by cultured human colonic mucosa: indication for possible presence of E mast cells.
An association between the release of histamine and chondroitin sulfate E proteoglycan (PG) was demonstrated in human colonic… 
1985
1985
Biosynthesis of heparin. Effects of n-butyrate on cultured mast cells.
1983
1983
Regeneration of rat mast cells after histamine secretion: changes in histidine decarboxylase activity and heparin synthesis.
Histidine decarboxylase activity in rat peritoneal mast cells is depressed temporarily after histamine secretion induced by… 
1981
1981
Effect of cycloheximide, beta-D-xylosides and beta-D-galactosides on heparin biosynthesis in mouse mastocytoma.
Heparin biosynthesis has been investigated with mouse mastocytoma in vitro. Minced tumour tissue catalysed the incorporation of… 
1976
1976
[Role of complex thrombin-heparin formation in the clearance of thrombin in the blood stream and the role of liver and lungs in the absorption of heparin-complexes (author's transl)].
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