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heparin biosynthetic process

Known as: heparin formation, heparin biosynthesis, heparin synthesis 
The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000… Expand
National Institutes of Health

Papers overview

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2017
2017
Liposomal encapsulation is a useful drug delivery strategy for small molecules, especially chemotherapeutic agents such as… Expand
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2011
2011
Background: NDST1 and 2 are isoenzymes taking part in heparan sulfate and heparin N-sulfation during biosynthesis. Results: NDST1… Expand
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2011
2011
Heparosan is a polysaccharide, which serves as the critical precursor in heparin biosynthesis and chemoenzymatic synthesis of… Expand
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Highly Cited
2010
Highly Cited
2010
Heparosan is an acidic polysaccharide natural product, which serves as the critical precursor in heparin biosynthesis and in the… Expand
2006
2006
Biosynthesis of heparin, a mast cell–derived glycosaminoglycan with widespread importance in medicine, has not been fully… Expand
Highly Cited
2001
Highly Cited
2001
The tumor suppressors EXT1 and EXT2 are associated with hereditary multiple exostoses and encode bifunctional… Expand
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Highly Cited
1991
Highly Cited
1991
We investigated the effects of a newly recognized multifunctional growth factor, the c-kit ligand stem cell factor (SCF), on… Expand
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Highly Cited
1986
Highly Cited
1986
An association between the release of histamine and chondroitin sulfate E proteoglycan (PG) was demonstrated in human colonic… Expand
1985
1985
Murine mastocytoma cells were incubated in vitro with inorganic [35S]sulfate, in the absence or presence of 2.5 mM n-butyrate… Expand
1981
1981
Heparin biosynthesis has been investigated with mouse mastocytoma in vitro. Minced tumour tissue catalysed the incorporation of… Expand