guanylate

 
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
The AIM2 inflammasome detects double-stranded DNA in the cytosol and induces caspase-1-dependent pyroptosis as well as release of… (More)
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Highly Cited
2014
Highly Cited
2014
IFN receptor signaling induces cell-autonomous immunity to infections with intracellular bacterial pathogens. Here, we… (More)
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Highly Cited
2014
Highly Cited
2014
Lipopolysaccharide from Gram-negative bacteria is sensed in the host cell cytoplasm by a non-canonical inflammasome pathway that… (More)
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Highly Cited
2013
Highly Cited
2013
IFN-γ orchestrates the host response against intracellular pathogens. Members of the guanylate binding proteins (GBP) comprise… (More)
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Review
2011
Review
2011
Originally identified by their unusual ability to bind guanosine monophosphate (GMP) nucleotide agarose, the guanylate-binding… (More)
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Highly Cited
2009
Highly Cited
2009
Homeostatic sensory systems detect small deviations in temperature, water balance, pH, and energy needs to regulate adaptive… (More)
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Highly Cited
2006
Highly Cited
2006
Interferons are immunomodulatory cytokines that mediate anti-pathogenic and anti-proliferative effects in cells. Interferon… (More)
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Highly Cited
2003
Highly Cited
2003
Expression of the large GTPase guanylate binding protein-1 (GBP-1) is induced by inflammatory cytokines (ICs) in endothelial… (More)
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Highly Cited
2000
Highly Cited
2000
Interferon-γ is an immunomodulatory substance that induces the expression of many genes to orchestrate a cellular response and… (More)
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Highly Cited
1991
Highly Cited
1991
The gene encoding a 67-kDa cytoplasmic guanylate-binding protein (GBP) is transcriptionally induced in cells exposed to… (More)
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