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guanylate cyclase activator activity

Known as: guanylin 
Binds to and increases the activity of guanylate cyclase. [GOC:mah]
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Intestinal enteroendocrine cells are critical to central regulation of caloric consumption, since they activate hypothalamic… Expand
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Highly Cited
2007
Highly Cited
2007
The mammalian main olfactory epithelium (MOE) recognizes and transduces olfactory cues through a G protein-coupled, cAMP… Expand
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Review
2004
Review
2004
  • L. Forte
  • Pharmacology & therapeutics
  • 2004
  • Corpus ID: 5731755
Guanylin, uroguanylin, and the bacterial heat-stable enterotoxin (ST) peptides comprise a new family of cyclic guanosine 3'-5… Expand
Review
2004
Review
2004
  • A. Vaandrager
  • Molecular and Cellular Biochemistry
  • 2004
  • Corpus ID: 20240066
Guanylyl cyclase C (GC-C) was found to function as the principal receptor for heat-stable enterotoxins (STa), major causative… Expand
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Highly Cited
2000
Highly Cited
2000
The enteric peptides, guanylin and uroguanylin, are local regulators of intestinal secretion by activation of receptor-guanylate… Expand
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Highly Cited
1994
Highly Cited
1994
Heat‐stable enterotoxins (STa) produced by pathogenic bacteria induce profound salt and water secretion in the gut, leading to… Expand
Highly Cited
1994
Highly Cited
1994
Guanylin, a peptide homologue of the bacterial heat-stable enterotoxins (ST), is an endogenous activator of guanylate cyclase C… Expand
Highly Cited
1994
Highly Cited
1994
Guanylin, a bioactive peptide, has recently been isolated from the intestine; this peptide activates intestinal guanylate cyclase… Expand
Highly Cited
1993
Highly Cited
1993
The intestinal hormone guanylin and bacterial heat-stable enterotoxins (STs) are members of a peptide family that activates… Expand
Highly Cited
1992
Highly Cited
1992
Guanylin is a recently discovered endogenous activator of intestinal guanylate cyclase that was purified from intestinal tissue… Expand