grazoprevir

Known as: (1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropanesulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
To the Editor: Waiting times for kidney transplants exceed 3 to 5 years in many parts of the United States.1 Yet more than 500… (More)
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2017
2017
BACKGROUND & AIMS Patients infected with hepatitis C virus (HCV) genotype 1, 4, or 6, with or without cirrhosis, previously… (More)
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2017
2017
BACKGROUND & AIMS Elbasvir (an NS5A inhibitor) and grazoprevir (an NS3/4A protease inhibitor) are direct-acting antiviral agents… (More)
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2017
2017
BACKGROUND & AIMS Persons with hepatitis C virus (HCV) infection are at risk of progressive liver disease, cirrhosis, and… (More)
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Review
2016
Review
2016
A fixed-dose combination tablet of the hepatitis C virus (HCV) NS5A inhibitor elbasvir and the HCV NS3/4A protease inhibitor… (More)
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2016
2016
BACKGROUND The phase 2 C-SALVAGE study (Hepatitis C-Salvage Study for Patients who Failed DAA/PR Therapy) demonstrated a 96.2… (More)
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2016
2016
The selection of resistance-associated variants (RAVs) against single agents administered to patients chronically infected with… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Chronic hepatitis C virus (HCV) infection in patients with stage 4-5 chronic kidney disease increases the risk of… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Hepatitis C virus (HCV) infection is a leading cause of morbidity and mortality in patients with HIV-1. The C-EDGE CO… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND & AIMS The Phase-2 C-SALVAGE study evaluated an investigational interferon-free combination of grazoprevir (a NS3/4A… (More)
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