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goadsporin

National Institutes of Health

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Peptides

Papers overview

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2017
2017
Total Synthesis of the Post-translationally Modified Polyazole Peptide Antibiotic Goadsporin.
The structurally unique polyazole antibiotic goadsporin contains six heteroaromatic oxazole and thiazole rings integrated into a… 
2016
2016
In vivo and In vitro reconstitution of the dehydroalanine biosynthesis in goadsporin, a linear azole containing RiPP
2015
2015
Total synthesis of CPI-2081, breitfussin B and synthetic studies towards myriastramide C and goadsporin
Natural products have been the source and inspiration of numerous drugs. However, as they need to be isolated from natural… 
2014
2014
Genetic approaches to generate hyper-producing strains of goadsporin: the relationships between productivity and gene duplication in secondary metabolite biosynthesis
Improving the productivity of secondary metabolites is highly beneficial for the utilization of natural products. Here, we found… 
2005
2005
Characterization of the Biosynthetic Gene Cluster of Goad-sporin which Promote Secondary Metabolism and Sporulation in Actinomycetes
Goadsporin which was isolated from Streptomyces sp. TP-A0584 is a 19-amino-acid polypeptide containing four oxazole and two… 
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