Skip to search formSkip to main contentSkip to account menu

glypican 3

Known as: Glypican-3 
National Institutes of Health

Related topics

Related topics

4 relations
GPC3 geneGPC3 wt Allele

Narrower (1)

GPC3 protein, human

Broader (1)

Glypican

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Diagnostic performance of alpha-fetoprotein, lens culinaris agglutinin-reactive alpha-fetoprotein, des-gamma carboxyprothrombin, and glypican-3 for the detection of hepatocellular carcinoma: a…
BackgroundDiagnosis of early-stage hepatocellular carcinoma (HCC) followed by curative resection or liver transplantation offers… 
2010
2010
Up-regulation of glypican-3 in human hepatocellular carcinoma.
AIM To investigate the expression and significance of glypican-3 (GPC3) in human hepatocellular carcinoma (HCC). MATERIALS AND… 
2010
2010
Glypican-3 reexpression regulates apoptosis in murine adenocarcinoma mammary cells modulating PI3K/Akt and p38MAPK signaling pathways
Glypican-3 (GPC3) is a proteoglycan involved in proliferation and cell survival. Several reports demonstrated that GPC3 is… 
2009
2009
Discriminating hepatocellular carcinoma from metastatic carcinoma on fine‐needle aspiration biopsy of the liver: The utility of immunocytochemical panel
The cytomorphologic features of hepatocellular carcinoma (HCC) in fine‐needle aspiration (FNA) biopsy are well described. However… 
Highly Cited
2009
Highly Cited
2009
Utility of glypican‐3 and survivin in differentiating hepatocellular carcinoma from benign and preneoplastic hepatic lesions and metastatic carcinomas in liver fine‐needle aspiration biopsies
Glypican‐3 (GPC‐3), a membrane‐anchored heparin sulfate proteoglycan, has been shown to be expressed in ∼80% of hepatocellular… 
Review
2008
Review
2008
[Usefulness of a novel oncofetal antigen, glypican-3, for diagnosis and immunotherapy of hepatocellular carcinoma].
We identified glypican-3 (GPC3), as a novel oncofetal antigen, overexpressed specifically in hepatocellular carcinoma (HCC) and… 
Highly Cited
2005
Highly Cited
2005
Upregulation of Glypican‐3 expression in hepatocellular carcinoma but downregulation in cholangiocarcinoma indicates its differential diagnosis value in primary liver cancers
Abstract: Background/Aim: Expression alteration of Glypican‐3 (GPC3) is associated with several malignancies and has been… 
Highly Cited
2005
Highly Cited
2005
Recent developments in the first detection of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) ranks fifth in frequency of cancers worldwide. The main aetiological factor is hepatitis B virus… 
2004
2004
Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells
Elevated expression of the heparan sulphate proteoglycan glypican-3 (GPC3) was found on mRNA and protein levels in the atypical… 
2003
2003
Growth promotion of HepG2 hepatoma cells by antisense-mediated knockdown of glypican-3 is independent of insulin-like growth factor 2 signaling
Glypican-3 (GPC3) encodes a cell-surface heparan-sulfate proteoglycan and its expression is frequently silenced in ovarian cancer… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)