glycinexylidide

Known as: 2-amino-2',6'-acetoxylidide, glycylxylidide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
02419732017

Papers overview

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2012
2012
BACKGROUND Lidocaine exerts antinociceptive effects when applied systemically. The mechanisms are not fully understood but… (More)
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2004
2004
OBJECTIVES This study was designed (1) to evaluate the effect of a cytochrome P450 (CYP) 1A2 inhibitor, fluvoxamine, on the… (More)
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2004
2004
OBJECTIVE To determine the influence of a low-dose constant rate infusion (LCRI; 50 microg kg(-1) minute(-1)) and high-dose CRI… (More)
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2000
2000
BACKGROUND AND OBJECTIVES The purpose of this study was to evaluate the effect of age on the pharmacokinetics of lidocaine after… (More)
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1988
1988
The modulated receptor hypothesis states that sodium channels have a specific receptor for antiarrhythmic drugs. Therefore, two… (More)
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1984
1984
Current theories envision recovery from local anesthetic block of sodium channels via slow hydrophilic and fast hydrophobic paths… (More)
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1984
1984
No validated method exists for measuring lidocaine and its metabolites in myocardial tissue. We modified a previously described… (More)
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1978
1978
It has been shown that the antiarrhythmic and toxic effects of lidocaine may be in part dependent on its two active metabolites… (More)
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1975
1975
Glycinexylidide (GX) is a metabolite of lidocaine that is frequently present in mug/ml concentrations in the plasma of patients… (More)
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