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glycinexylidide
Papers overview
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE
To determine the influence of a low-dose constant rate infusion (LCRI; 50 microg kg(-1) minute(-1)) and high-dose CRI… Expand
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2004
2004
OBJECTIVES
This study was designed (1) to evaluate the effect of a cytochrome P450 (CYP) 1A2 inhibitor, fluvoxamine, on the… Expand
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1989
1989
The metabolism of lidocaine was studied using rat liver microsomes or a reconstituted lidocaine monooxygenase system with one of… Expand
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1988
1988
The modulated receptor hypothesis states that sodium channels have a specific receptor for antiarrhythmic drugs. Therefore, two… Expand
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1984
1984
No validated method exists for measuring lidocaine and its metabolites in myocardial tissue. We modified a previously described… Expand
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1983
1983
Summary Lidocaine, a highly effective antiarrhythmic agent, is metabolized to monethylglycylxylidide (MEGX) and glycylxylidide… Expand
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1979
1979
We investigated the metabolism of lidocaine to its active metabolites--monoethylglycinexylidide (MEGX) and glycinexylidide (GX… Expand
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1978
1978
It has been shown that the antiarrhythmic and toxic effects of lidocaine may be in part dependent on its two active metabolites… Expand
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1975
1975
Glycinexylidide (GX) is a metabolite of lidocaine that is frequently present in mug/ml concentrations in the plasma of patients… Expand
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1974
1974
Gas-liquid chromatographic methods have been developed for the estimation of lignocaine and its metabolites ethylglycylxylidide… Expand
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