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glycine hydroxymethyltransferase activity

Known as: 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity, serine hydroxymethyltransferase activity, allothreonine aldolase activity 
Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. [EC:2.1.2.1]
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection.
Highly Cited
2009
Highly Cited
2009
Arabidopsis Photorespiratory Serine Hydroxymethyltransferase Activity Requires the Mitochondrial Accumulation of Ferredoxin-Dependent Glutamate Synthase[W]
The dual affinity of ribulose-1,5-bisphosphate carboxylase/oxygenase for O2 and CO2 results in the net loss of fixed carbon and… 
2005
2005
Low serine hydroxymethyltransferase activity in the human placenta has important implications for fetal glycine supply.
Glycine is essential for fetal development, but in both sheep and human pregnancy, little is transported directly from the mother… 
Highly Cited
1990
Highly Cited
1990
Regulation of the Escherichia coli glyA gene by the purR gene product
The purine regulon repressor protein, PurR, was shown to be a purine component involved in glyA regulation in Escherichia coli… 
1989
1989
A binding assay for serine hydroxymethyltransferase.
1985
1985
Characterization of a cis-acting regulatory mutation that maps at the distal end of the Escherichia coli glyA gene
We have isolated a phage Mu cts-generated glyA mutant with only 30% of the normal level of serine hydroxymethyltransferase… 
1980
1980
Effect of methionine, glycine and serine on serine hydroxymethyltransferase activity in rat glioma and human neuroblastoma cells
Human neuroblastoma SK‐N‐SH‐SY5Y (5Y) and rat glioma (C6) cells were cultured with supplemental methionine, glycine, or serine… 
1979
1979
Serine hydroxymethyltransferase activity and serine incorporation in leukocytes.
Studies of serine hydroxymethyltransferase activity in extracts of leukocytes from normal and leukemic subjects showed that the… 
1972
1972
Genetics of somatic mammalian cells. XV. Evidence for linkage between human genes for lactic dehydrogenase B and serine hydroxymethylase
Chinese hamster ovary cells with a deficiency in Serine Hydroxymethylase which produces a specific glycine auxotrophy (gly− A… 
Highly Cited
1965
Highly Cited
1965
Glycine Synthesis and Metabolism in Escherichia coli
Pizer, Lewis I. (University of Pennsylvania, Philadelphia). Glycine synthesis and metabolism in Escherichia coli. J. Bacteriol… 
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