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Protection by Anti-β-Glucan Antibodies Is Associated with Restricted β-1,3 Glucan Binding Specificity and Inhibition of Fungal Growth and Adherence
Anti-β-glucan antibodies elicited by a laminarin-conjugate vaccine confer cross-protection to mice challenged with major fungal pathogens such as Candida albicans, Aspergillus fumigatus and… Expand
Pantetheinase activity of membrane‐bound Vanin‐1: lack of free cysteamine in tissues of Vanin‐1 deficient mice
Pantetheinase (EC 3.5.1.‐) is an ubiquitous enzyme which in vitro has been shown to recycle pantothenic acid (vitamin B5) and to produce cysteamine, a potent anti‐oxidant. We show that the Vanin‐1… Expand
The plant oncogene rolD encodes a functional ornithine cyclodeaminase
- M. Trovato, B. Maras, F. Linhares, P. Costantino
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 30 October 2001
The plant oncogene rolD stimulates the reproductive phase transition in plants. We define here the function of its gene product. We show that the RolD protein bears sequence homology with ornithine… Expand
Streptomyces griseus aminopeptidase: X-ray crystallographic structure at 1.75 A resolution.
The X-ray crystal structure of the enzyme Streptomyces griseus aminopeptidase (SGAP) has been determined in its double zinc form to 1.75 A resolution, in its apo-enzyme from (zinc removed) to 2.1 A… Expand
Proteomic profiling of PrP27-30-enriched preparations extracted from the brain of hamsters with experimental scrapie.
Transmissible spongiform encephalopathies (TSEs) are neurodegenerative disorders characterized by the accumulation in the CNS of a pathological conformer (PrP(TSE)) of the host-encoded cellular prion… Expand
Cellular nucleic acid binding protein binds a conserved region of the 5' UTR of Xenopus laevis ribosomal protein mRNAs.
- L. Pellizzoni, F. Lotti, B. Maras, P. Pierandrei-Amaldi
- Biology, Medicine
- Journal of molecular biology
- 1 March 1997
Vertebrate ribosomal protein mRNAs share structural features in the 5' untranslated region implicated in the control of their translation. A pyrimidine tract, at the 5' end, is considered the common… Expand
The amino acid sequence of the aspartate aminotransferase from baker's yeast (Saccharomyces cerevisiae).
1. The single (cytosolic) aspartate aminotransferase was purified in high yield from baker's yeast (Saccharomyces cerevisiae). 2. Amino-acid-sequence analysis was carried out by digestion of the… Expand
Structural and Functional Analysis of the N-Terminal Extracellular Region of β-Dystroglycan
Abstract A protein fragment corresponding to the mouse β-dystroglycan N-terminal extracellular region from position 654 to 750, β-DG(654–750) was recombinantly expressed in BL21(DE3) Escherichia coli… Expand
Structural Analysis of Saposin C and B
- A. Vaccaro, R. Salvioli, +7 authors P. Pucci
- Biology, Chemistry
- The Journal of Biological Chemistry
- 28 April 1995
Saposins A, B, C, and D are a group of homologous glycoproteins derived from a single precursor, prosaposin, and apparently involved in the stimulation of the enzymatic degradation of sphingolipids… Expand
Identification of a glucan-associated enolase as a main cell wall protein of Candida albicans and an indirect target of lipopeptide antimycotics.
- L. Angiolella, M. Facchin, A. Stringaro, B. Maras, N. Simonetti, A. Cassone
- Biology, Medicine
- The Journal of infectious diseases
- 1 March 1996
Growth-subinhibitory nonlytic doses of cilofungin (lipopeptide antibiotic affecting (1,3)-beta-D-glucan synthesis) inhibited the incorporation of 46- to 48-kDa glucan-associated (46K) protein into… Expand