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glycine binding
Known as:
Gly binding
, aminoacetic acid binding
, aminoethanoic acid binding
Interacting selectively and non-covalently with glycine, aminoethanoic acid. [GOC:ai]
National Institutes of Health
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2011
2011
Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for positron emission tomography imaging of the glycine binding site of the N-methyl-D…
A. Bauman
,
M. Piel
,
+5 authors
F. Rösch
2011
Corpus ID: 7294954
The N-methyl- d-aspartate (NMDA) receptor as a type of ionotropic glutamatergic receptors is essential for physiological…
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2009
2009
The Integrity of the Glycine Co-agonist Binding Site of N-Methyl-d-aspartate Receptors Is a Functional Quality Control Checkpoint for Cell Surface Delivery*
Anna V. Kenny
,
Sarah L. Cousins
,
Leonor Pinho
,
F. Anne Stephenson
Journal of Biological Chemistry
2009
Corpus ID: 40196836
N-Methyl-d-aspartate receptors are a subclass of ligand-gated, heteromeric glutamatergic neurotransmitter receptors whose cell…
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2003
2003
Expression of a soluble glycine binding domain of the NMDA receptor in Escherichia coli.
R. Neugebauer
,
H. Betz
,
J. Kuhse
Biochemical and Biophysical Research…
2003
Corpus ID: 6337017
2003
2003
CoMFA and homology-based models of the glycine binding site of N-methyl-d-aspartate receptor.
I. Tikhonova
,
I. Baskin
,
V. Palyulin
,
N. Zefirov
Journal of Medicinal Chemistry
2003
Corpus ID: 43298279
Homology modeling was used to build 3D models of the N-methyl-d-aspartate (NMDA) receptor glycine binding site on the basis of an…
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1999
1999
Substituted analogues of GV150526 as potent glycine binding site antagonists in animal models of cerebral ischemia.
R. Di Fabio
,
N. Conti
,
+6 authors
R. Barnaby
Journal of Medicinal Chemistry
1999
Corpus ID: 39982828
A series of analogues of the indole-2-carboxylate GV150526, currently in clinical trials as a potential neuroprotective agent for…
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1999
1999
Cycloalkyl Indole‐2‐Carboxylates as Useful Tools for Mapping the "North‐Eastern" Region of the Glycine Binding Site Associated with the NMDA Receptor
F. Micheli
,
R. Di Fabio
,
+11 authors
F. van Amsterdam
Archiv der Pharmazie
1999
Corpus ID: 19996215
A novel series of indole‐2‐carboxylate analogues of GV150526 (1) in which the terminal phenyl ring belonging to the side chain…
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1998
1998
Glycine derivatives of imidazolones as potential ligands of glycine binding site of NMDA receptors. Part 1.
K. Kieć‐Kononowicz
,
J. Karolak‐Wojciechowska
,
J. Handzlik
Acta Poloniae Pharmaceutica - Drug Research
1998
Corpus ID: 45692718
The series of glycine derivatives of diphenyl or (un)substituted arylidene imidazolones was designed and obtained as potential…
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1997
1997
Analysis of the glycine binding domain of the NMDA receptor channel zeta 1 subunit.
S. Uchino
,
S. Nakajima‐Iijima
,
K. Okuda
,
M. Mishina
,
S. Kawamoto
NeuroReport
1997
Corpus ID: 19666053
In an attempt to examine glycine binding domain of the zeta 1 subunit of the mouse N-methyl-D-aspartate (NMDA) receptor channel…
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1994
1994
The glycine binding site of the NMDA receptor: involvement in neurodegeneration and new approach for neuroprotection.
J. Hartmann
,
G. Ransmayr
,
P. Riederer
Journal of neural transmission. Supplementum
1994
Corpus ID: 228135
Excitatory amino acids may have a neurotoxic effect in acute and chronic neurodegenerative diseases. Glutamate mediated Ca-influx…
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1991
1991
Sulfhydryl Groups Modulate the Allosteric Interaction Between Glycine Binding Sites at the Inhibitory Glycine Receptor
A. Ruiz-Gómez
,
Clara Fernández-Shaw
,
+4 authors
F. Mayor
Journal of Neurochemistry
1991
Corpus ID: 25781229
Abstract: We have investigated the effect of chemical reagents that modify sulfhydryl groups on the ligand binding properties of…
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