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glycine amide

Known as: 2-aminoacetamide, glycinamide 
 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
SummaryAim of the studymRNA expression of genes involved in the mechanism of action of pemetrexed was correlated with in vitro… Expand
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Highly Cited
2005
Highly Cited
2005
The phylogenetic position of turtles is a currently controversial issue. Recent molecular studies rejected a traditional view… Expand
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Review
2004
Review
2004
  • Alex A. Adjei
  • Clinical cancer research : an official journal of…
  • 2004
  • Corpus ID: 31467685
Pemetrexed (ALIMTA, LY231514, MTA) is a novel antimetabolite that inhibits at least three enzymes involved in the folate pathway… Expand
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Highly Cited
2003
Highly Cited
2003
We have studied the molecular basis of drug resistance in human CCRF-CEM leukemia cells exposed to high dose intermittent pulses… Expand
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Review
2002
Review
2002
Pemetrexed is a new-generation antifolate that in its higher polyglutamyl forms is a potent, direct inhibitor of thymidylate… Expand
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Highly Cited
2001
Highly Cited
2001
We have developed, experimentally implemented, and modeled in silico a methodology named SCRATCHY that enables the combinatorial… Expand
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Highly Cited
1999
Highly Cited
1999
We present a methodology, termed incremental truncation for the creation of hybrid enzymes (ITCHY), that creates combinatorial… Expand
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Highly Cited
1999
Highly Cited
1999
Purpose: To determine toxicities, maximally tolerated dose (MTD), pharmacokinetic profile, and potential antitumor activity of… Expand
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Review
1998
Review
1998
It is almost 50 years since antimetabolites were first found to have clinical antitumour activity, with Farber's discovery that… Expand
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Highly Cited
1989
Highly Cited
1989
5,10-Dideazatetrahydrofolate (DDATHF) is a new antimetabolite designed as an inhibitor of folate metabolism at sites other than… Expand
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