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glycidamide

Known as: oxiranecarboxamide, glycidic acid amide, oxirane-2-carboxamide 
National Institutes of Health

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Broader (1)

Epoxy Compounds

Papers overview

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2015
2015
Comprehensive profiling of mercapturic acid metabolites from dietary acrylamide as short-term exposure biomarkers for evaluation of toxicokinetics in rats and daily internal exposure in humans using…
Review
2012
Review
2012
Critical review of dose-response options for F344 rat mammary tumors for acrylamide - additional insights based on mode of action.
2011
2011
Excretion of 2,3-dihydroxy-propionamide (OH-PA), the hydrolysis product of glycidamide, in human urine after single oral dose of deuterium-labeled acrylamide
A dose of 0.99 mg d3-acrylamide (d3-AA) (13.2 μg/kg body weight) was ingested by a healthy male volunteer. Urine samples were… 
2008
2008
Genotoxicity of glycidamide in comparison to 3-N-nitroso-oxazolidin-2-one.
Acrylamide (AA) is generated by thermal processing of foods, depending on processing conditions and precursor availability. AA is… 
2008
2008
Development of a stable isotope dilution assay for the quantitation of glycidamide and its application to foods and model systems.
On the basis of a stable isotope dilution assay and derivatization with 2-mercaptobenzoic acid, the presence of the carcinogenic… 
2007
2007
Effects of perinatal exposure to acrylamide and glycidamide on intestinal tumorigenesis in Min/+ mice and their wild-type litter mates.
The tumorigenic capacity of acrylamide (AA) in the intestine of C57BL/6J Min/+ mice, as well as in their wild-type (wt) litter… 
Highly Cited
2006
Highly Cited
2006
Metabolism of acrylamide to glycidamide and their cytotoxicity in isolated rat hepatocytes: protective effects of GSH precursors
Acrylamide (AA) is a widely studied industrial chemical that is neurotoxic, mutagenic to somatic and germ cells, and carcinogenic… 
2004
2004
Characterization of the adducts formed in the reactions of glycidamide with thymidine and cytidine.
Glycidamide (GA) is a mutagenic epoxide metabolite of acrylamide (AM), a high production chemical with many industrial uses… 
Highly Cited
2001
Highly Cited
2001
The multiplicative model for cancer risk assessment: applicability to acrylamide.
According to a multiplicative model for prediction of cancer risk for genotoxic agents the incremental cancer risk is, for low… 
1992
1992
Linear versus nonlinear models for hemoglobin adduct formation by acrylamide and its metabolite glycidamide: implications for risk estimation.
Hemoglobin cysteine adduct levels formed by acrylamide (AA) and its epoxide metabolite glycidamide (GA) as previously determined… 
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