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glucocorticoid biosynthetic process

Known as: glucocorticoid biosynthesis, glucocorticoid anabolism, glucocorticoid synthesis 
The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. [ISBN… 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis
Although tumor necrosis factor (α) (TNF) exerts proinflammatory activities in a variety of diseases, including inflammatory bowel… 
Highly Cited
2006
Highly Cited
2006
The nuclear receptor LRH-1 critically regulates extra-adrenal glucocorticoid synthesis in the intestine
The nuclear receptor liver receptor homologue-1 (LRH-1, NR5A2) is a crucial transcriptional regulator of many metabolic pathways… 
Highly Cited
2005
Highly Cited
2005
11β-Hydroxysteroid Dehydrogenase Expression and Glucocorticoid Synthesis Are Directed by a Molecular Switch during Osteoblast Differentiation
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) plays an important role in the prereceptor regulation of corticosteroids by… 
Highly Cited
2003
Highly Cited
2003
Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids.
Leptin is essential for the establishment of pregnancy and appears to promote fetal growth, but the mechanisms regulating fetal… 
Highly Cited
2002
Highly Cited
2002
Glucocorticoid Involvement in Memory Formation in a Rat Model for Traumatic Memory
Contextual fear conditioning under training conditions involving high stressor intensities has been proposed as an animal model… 
Highly Cited
2002
Highly Cited
2002
Leptin Receptor Expression in the Rat Placenta: Changes in Ob-Ra, Ob-Rb, and Ob-Re with Gestational Age and Suppression by Glucocorticoids1
Abstract Leptin, the hormone product of the ob gene, has recently been implicated as an important player in the complex hormonal… 
Highly Cited
1998
Highly Cited
1998
Role of the hypothalamic pituitary adrenal axis and IL-6 in stress-induced reactivation of latent herpes simplex virus type 1.
Hyperthermic stress induces reactivation of herpes simplex virus type 1 (HSV-1) in latently infected mice and also stimulates… 
Highly Cited
1996
Highly Cited
1996
In vivo regulation of peripheral-type benzodiazepine receptor and glucocorticoid synthesis by Ginkgo biloba extract EGb 761 and isolated ginkgolides.
Glucocorticoid excess has broad pathogenic potential including neurotoxicity, neuroendangerment, and immunosuppression… 
Highly Cited
1993
Highly Cited
1993
Maternal separation in neonatal rats elicits activation of the hypothalamic-pituitary-adrenocortical axis: A putative role for corticotropin-releasing factor
Highly Cited
1986
Highly Cited
1986
Inhibition of immunoreactive corticotropin-releasing factor secretion into the hypophysial-portal circulation by delayed glucocorticoid feedback.
Nitroprusside-induced hypotension evokes ACTH secretion which is primarily mediated by enhanced secretion of immunoreactive… 
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