glucocorticoid biosynthetic process

Known as: glucocorticoid biosynthesis, glucocorticoid anabolism, glucocorticoid synthesis 
The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. [ISBN… (More)
National Institutes of Health

Papers overview

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2015
2015
Reducing Social Stress Elicits Emotional Contagion of Pain in Mouse and Human Strangers
Empathy for another's physical pain has been demonstrated in humans [1] and mice [2]; in both species, empathy is stronger… (More)
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Highly Cited
2010
Highly Cited
2010
TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis
Although tumor necrosis factor (alpha) (TNF) exerts proinflammatory activities in a variety of diseases, including inflammatory… (More)
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Highly Cited
2009
Highly Cited
2009
Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress
Recent work from our laboratory and others has shown that certain stressors increase expression of the pro-inflammatory cytokine… (More)
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Highly Cited
2008
Highly Cited
2008
SR-BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance.
Septic shock results from an uncontrolled inflammatory response, mediated primarily by LPS. Cholesterol transport plays an… (More)
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Highly Cited
2007
Highly Cited
2007
LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease.
Liver receptor homolog-1 (LRH-1) is a nuclear receptor involved in intestinal lipid homeostasis and cell proliferation. Here we… (More)
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2003
2003
Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids.
Leptin is essential for the establishment of pregnancy and appears to promote fetal growth, but the mechanisms regulating fetal… (More)
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2002
2002
Glucocorticoid involvement in memory formation in a rat model for traumatic memory.
Contextual fear conditioning under training conditions involving high stressor intensities has been proposed as an animal model… (More)
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Highly Cited
1997
Highly Cited
1997
Hypertension induced by foetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis.
BACKGROUND Hypertension and coronary heart disease are programmed by maternal undernutrition in utero. The feeding of low-protein… (More)
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1993
1993
Maternal separation in neonatal rats elicits activation of the hypothalamic-pituitary-adrenocortical axis: A putative role for corticotropin-releasing factor
Stress elicits activation of the hypothalamic-pituitary-adrenocortical (HPA) axis. Hypothalamic neurohormones, including… (More)
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Highly Cited
1992
Highly Cited
1992
Rapid regulation of corticotropin-releasing hormone gene transcription in vivo.
Regulation of corticotropin-releasing hormone (CRH) gene expression in vivo was assessed via in situ hybridization histochemistry… (More)
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