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gingipain

National Institutes of Health

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argingipain, Porphyromonas gingivalis

Papers overview

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2018
2018
Lipoprotein modifications by gingipains of Porphyromonas gingivalis
Abstract Background and Objective Several studies have shown an association between periodontitis and cardiovascular disease (CVD… 
Highly Cited
2017
Highly Cited
2017
Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids
BACKGROUND AND OBJECTIVE Porphyromonas gingivalis is considered a major pathogen of chronic periodontitis, which also may be… 
Highly Cited
2015
Highly Cited
2015
Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas gingivalis
Aspiration pneumonia is a life-threatening infectious disease often caused by oral anaerobic and periodontal pathogens such as… 
Highly Cited
2009
Highly Cited
2009
Kinin Danger Signals Proteolytically Released by Gingipain Induce Fimbriae-Specific IFN-γ- and IL-17-Producing T Cells in Mice Infected Intramucosally with Porphyromonas gingivalis1
Porphyromonas gingivalis, a Gram-negative bacterium that causes periodontitis, activates the kinin system via the cysteine… 
Review
2008
Review
2008
Gingipain-dependent interactions with the host are important for survival of Porphyromonas gingivalis.
Porphyromonas gingivalis, a major periodontal pathogen, must acquire nutrients from host derived substrates, overcome oxidative… 
Highly Cited
2006
Highly Cited
2006
Gingipains from Porphyromonas gingivalis W83 Synergistically Disrupt Endothelial Cell Adhesion and Can Induce Caspase-Independent Apoptosis
ABSTRACT We have shown previously that gingipains from Porphyromonas gingivalis W83 can induce cell detachment, cell adhesion… 
2006
2006
The HA2 haemagglutinin domain of the lysine-specific gingipain (Kgp) of Porphyromonas gingivalis promotes micro-oxo bishaem formation from monomeric iron(III) protoporphyrin IX.
The lysine- and arginine-specific gingipains (Kgp, and RgpA and RgpB) are the major proteinases produced by the black-pigmented… 
Highly Cited
2001
Highly Cited
2001
Porphyromonas gingivalis Gingipains and Adhesion to Epithelial Cells
ABSTRACT Porphyromonas gingivalis is one of the principal organisms associated with adult periodontitis. Bacterial surface… 
Highly Cited
2001
Highly Cited
2001
Prevention of Porphyromonas gingivalis-Induced Oral Bone Loss following Immunization with Gingipain R1
ABSTRACT The arginine gingipains RgpA and RgpB of Porphyromonas gingivalis are well-documented virulence factors of this organism… 
Highly Cited
1997
Highly Cited
1997
Molecular Cloning and Characterization of Porphyromonas gingivalis Lysine-specific Gingipain
The proteinases of Porphyromonas gingivalis are key virulence factors in the etiology and progression of periodontal disease… 
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