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germacrene-A synthase activity

Known as: GAS, (+)-germacrene A synthase activity, (+)-(10R)-germacrene A synthase activity 
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate. [EC:4.2.3.23, RHEA:12519]
National Institutes of Health

Related topics

Related topics

1 relation
glutaryl-7-aminocephalosporanic-acid acylase activity

Papers overview

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Highly Cited
2017
Highly Cited
2017
The essential oil from Zanthoxylum monophyllum a potential mosquito larvicide with low toxicity to the non-target fish Gambusia affinis
The mosquito larvicidal activity of Zanthoxylum monophyllum leaf essential oil (EO) and its major chemical constituents was… 
2017
2017
Metabolic engineering of Saccharomyces cerevisiae for production of germacrene A, a precursor of beta-elemene
Beta-elemene, a sesquiterpene and the major component of the medicinal herb Curcuma wenyujin, has antitumor activity against… 
Highly Cited
2015
Highly Cited
2015
Volatiles composition and extraction kinetics from Schinus terebinthifolius and Schinus molle leaves and fruit
Highly Cited
2008
Highly Cited
2008
Chemical composition and antimicrobial activity of Momordica charantia seed essential oil.
Highly Cited
2006
Highly Cited
2006
Geosmin Biosynthesis in Streptomyces avermitilis. Molecular Cloning, Expression, and Mechanistic Study of the Germacradienol/Geosmin Synthase
Geosmin (1) is responsible for the characteristic odor of moist soil. The Gram-positive soil bacterium Streptomyces avermitilis… 
Highly Cited
2004
Highly Cited
2004
Mechanism and stereochemistry of the germacradienol/germacrene D synthase of Streptomyces coelicolor A3(2).
Incubation of farnesyl diphosphate (1, FPP) with recombinant germacradienol synthase from Streptomyces coelicolor A3(2) gave, in… 
Highly Cited
2002
Highly Cited
2002
Cloning and expression of sesquiterpene synthase genes from lettuce (Lactuca sativa L.).
Highly Cited
2000
Highly Cited
2000
The role of germacrene D as a precursor in sesquiterpene biosynthesis: investigations of acid catalyzed, photochemically and thermally induced rearrangements.
Highly Cited
1998
Highly Cited
1998
(+)-Germacrene A biosynthesis . The committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
The leaves and especially the roots of chicory (Cichorium intybus L. ) contain high concentrations of bitter sesquiterpene… 
Highly Cited
1998
Highly Cited
1998
Germacrene C synthase from Lycopersicon esculentum cv. VFNT cherry tomato: cDNA isolation, characterization, and bacterial expression of the multiple product sesquiterpene cyclase.
Germacrene C was found by GC-MS and NMR analysis to be the most abundant sesquiterpene in the leaf oil of Lycopersicon esculentum… 
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