Semantic Scholar uses AI to extract papers important to this topic.
The mevalonate pathway produces cholesterol and nonsterol isoprenoids, such as geranylgeraniol. In the brain, a fraction of… Expand We recently developed a genome‐length hepatitis C virus (HCV) RNA replication system (OR6) with luciferase as a reporter. The OR6… Expand ABSTRACT We examined the antibacterial activities against Staphylococcus aureus of three diterpenes, namely, geranylgeraniol… Expand The endoplasmic reticulum enzyme 3-hydroxy-3-methylglutaryl-CoA reductase produces mevalonate, which is converted to sterols and… Expand We examined the effects of four 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (pravastatin, simvastatin… Expand Nitrogen-containing bisphosphonates were shown to cause macrophage apoptosis by inhibiting enzymes in the biosynthetic pathway… Expand Recently, advances have been made in understanding the molecular mechanisms by which bisphosphonate drugs inhibit bone resorption… Expand Compounds derived from the isoprenoid/cholesterol biosynthetic pathway have recently been shown to have novel biological… Expand We examined the effect of fluvastatin, the first entirely synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor… Expand The reduction of geranylgeranylpyrophosphate to phytylpyrophosphate in spinach chloroplasts is described for the first time. The… Expand