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gentisamide

Known as: 2,5-dihydroxybenzamide 
National Institutes of Health

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Benzamides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
FT-IR and NMR spectroscopic studies of salicylic acid derivatives. I. Gentisamide -- a metabolite of salicylamide.
Gentisamide (GAM, 2,5-dihydroxybenzamide), a minor first-pass metabolite of salicylamide (SAM, 2-hydroxybenzamide), was studied… 
2002
2002
FTIR and NMR Spectroscopic Structural Studies of Gentisamide Isolated from Biological Material
Monitoring of drug metabolites is of toxicological, pharmacological and biomedical interest. Nowadays, NMR represents unique and… 
1991
1991
Bioavailability of aspirin and salicylamide following oral co-administration in human volunteers.
BC powder (I) is a commercially available analgesic containing the active ingredients aspirin and salicylamide. The kinetics of I… 
1988
1988
Competing pathways in drug metabolism. II. An identical, anterior enzymic distribution for 2- and 5-sulfoconjugation and a posterior localization for 5-glucuronidation of gentisamide in the rat liver
Gentisamide (2,5-dihydroxybenzamide, GAM), a substrate that forms two monosulfates at the 2 and 5 positions (GAM-2S and GAM-5S… 
1988
1988
3-Hydroxylation of salicylamide in mice.
Salicylamide is an important model compound for use in investigations concerning drug disposition. In this study the metabolic… 
1987
1987
High-performance liquid chromatographic method for the quantitation of salicylamide and its metabolites in biological fluids.
1987
1987
Depression of salicylamide glucuronidation by bacterial lipopolysaccharide.
The effect of lipopolysaccharide (LPS) on the urinary excretion of salicylamide (SAM) (10 mg/head) given orally to rats was… 
1985
1985
Pharmacodynamics of the hypnotic effect of salicylamide in rats.
Salicylamide (SAM) can produce sedation and sleep in humans and animals. To explore the potential utility of the drug as a… 
1983
1983
Determination of salicylamide and five metabolites in biological fluids by high-performance liquid chromatography.
Two high-performance liquid chromatographic (HPLC) assay procedures were developed for the determination of salicylamide and its… 
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