gene therapy

Known as: DNA Therapy, Gene Transfer Procedure, Intervention, Genetic 
Treatment that alters a gene. In studies of gene therapy for cancer, researchers are trying to improve the body's natural ability to fight the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Wiskott-Aldrich syndrome (WAS) is characterized by microthrombocytopenia, immunodeficiency, autoimmunity, and susceptibility to… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Aspergillus spp infection is a potentially lethal disease in patients with neutropenia or impaired neutrophil function… (More)
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Highly Cited
2009
Highly Cited
2009
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease resulting from the expansion of a glutamine repeat… (More)
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Highly Cited
2006
Highly Cited
2006
Retroviral and lentiviral vector integration into host-cell chromosomes carries with it a finite chance of causing insertional… (More)
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Highly Cited
2006
Highly Cited
2006
It has been recently shown that recombinant adeno-associated virus serotype 8 (rAAV8) is a robust alternative serotype vector… (More)
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Review
2003
Review
2003
Increases in efficiency have made naked DNA gene transfer a viable method for gene therapy. Intravascular delivery results in… (More)
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Highly Cited
2003
Highly Cited
2003
Replication-deficient human adenovirus type 5 (Ad5) can be produced to high titers in complementing cell lines, such as PER.C6… (More)
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Highly Cited
2002
Highly Cited
2002
Tissues from rhesus monkeys were screened by PCR for the presence of sequences homologous to known adeno-associated virus (AAV… (More)
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Highly Cited
2000
Highly Cited
2000
Severe combined immunodeficiency-X1 (SCID-X1) is an X-linked inherited disorder characterized by an early block in T and natural… (More)
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Highly Cited
1999
Highly Cited
1999
Hemophilia B is a severe X-linked bleeding diathesis caused by the absence of functional blood coagulation factor IX, and is an… (More)
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