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gene therapy

Known as: DNA Therapy, Gene Transfer Procedure, Intervention, Genetic 
Treatment that alters a gene. In studies of gene therapy for cancer, researchers are trying to improve the body's natural ability to fight the… 
National Institutes of Health

Related topics

Related topics

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Broader (4)

Biological Response Modifier TherapyGenetic TherapyTherapeutic proceduregenetic manipulation
CDISC SDTM Intervention Type TerminologyClinical Data Interchange Standards Consortium TerminologyGene Delivery SystemsGene Transfer

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Human Germline Interventions–Think First
Recent studies using gene editing tools such as CRISPR/Cas9 have shown an enormously broad spectrum of possible future… 
Review
2013
Review
2013
Huntington’s Disease: The Past, Present, and Future Search for Disease Modifiers
Huntington’s disease (HD) is an autosomal dominant genetic disorder that specifically causes neurodegeneration of striatal… 
Review
2012
Review
2012
Back to BAC: The Use of Infectious Clone Technologies for Viral Mutagenesis
Bacterial artificial chromosome (BAC) vectors were first developed to facilitate the propagation and manipulation of large DNA… 
2011
2011
Using Animal Models to Disentangle the Role of Genetic, Epigenetic, and Environmental Influences on Behavioral Outcomes Associated with Maternal Anxiety and Depression
The etiology of complex psychiatric disorders results from both genetics and the environment. No definitive environmental factor… 
Highly Cited
2006
Highly Cited
2006
WWOX--the FRA16D cancer gene: expression correlation with breast cancer progression and prognosis.
Highly Cited
2006
Highly Cited
2006
Gene Therapy Using Adenovirus-Mediated Full-length Anti-HER-2 Antibody for HER-2 Overexpression Cancers
Purpose: Therapeutic monoclonal antibody is increasingly applied in many clinical applications, although complicated technologies… 
Review
2004
Review
2004
Therapeutic potential of retroviral RNAi vectors
The ability of small interfering RNA (siRNA) to mediate gene-specific post-transcriptional silencing in mammalian cells will… 
Review
2003
Review
2003
Alphavirus vectors for vaccine production and gene therapy
Alphavirus vectors demonstrate high expression of heterologous proteins in a broad range of host cells. Replication-deficient as… 
1996
1996
Analysis of the relative level of gene expression from different retroviral vectors used for gene therapy.
We have analyzed the relative level of gene expression and viral titer from different types of retroviral vectors used for gene… 
1996
1996
Plasmoviruses: nonviral/viral vectors for gene therapy.
We have generated a chimeric gene transfer vector that combines the simplicity of plasmids with the infectivity and long-term… 
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