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gaboxadol

Known as: 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol, THIP 
 
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Extrasynaptic GABA(A) receptors (eGABARs) allow ambient GABA to tonically regulate neuronal excitability and are implicated as… Expand
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Highly Cited
2008
Highly Cited
2008
Fluctuating neurosteroid levels over the ovarian cycle modulate neuronal excitability through effects on GABA(A) receptors (GABA… Expand
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Highly Cited
2006
Highly Cited
2006
The neurotransmitter GABA mediates the majority of rapid inhibition in the CNS. Inhibition can occur via the conventional… Expand
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Highly Cited
2006
Highly Cited
2006
GABAA receptors (GABAARs) are usually formed by α, β, and γ or δ subunits. Recently, δ-containing GABAARs expressed in Xenopus… Expand
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Highly Cited
2006
Highly Cited
2006
THIP (4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol) is a selective GABA(A) receptor agonist with a preference for delta-subunit… Expand
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Highly Cited
1997
Highly Cited
1997
A key distinction between neural pacemaker and conventional network models for the generation of breathing rhythm in mammals is… Expand
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Highly Cited
1997
Highly Cited
1997
Ganaxolone (CCD 1042) is a 3b-methyl-substituted analog of the endogenous neuroactive steroid 3a-hydroxy-5a-pregnan20-one… Expand
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Highly Cited
1993
Highly Cited
1993
Recent studies have demonstrated that several specific types of acoustically-evoked GABA-mediated inhibition occur in neurons of… Expand
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Highly Cited
1985
Highly Cited
1985
Intracellular recordings from CA1 pyramidal cells in the hippocampal slice preparation were used to compare the action of… Expand
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Highly Cited
1985
Highly Cited
1985
The antinociceptive action of the gamma-aminobutyric acid (GABA) agonists THIP and baclofen was evaluated in mice using hot-plate… Expand
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