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furamidine

Known as: 2,5-BAPF, 2,5-bis(4-amidinophenyl)furan, 2,5-bis(4-guanylphenyl)furan 
National Institutes of Health

Papers overview

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2011
2011
ABSTRACT Current therapies for human African trypanosomiasis (HAT) are unsatisfactory and under threat from emerging drug… Expand
Highly Cited
2009
Highly Cited
2009
The antiparasitic activity of aromatic diamidine drugs, pentamidine and furamidine, depends on their entry into the pathogenic… Expand
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Review
2008
Review
2008
Designed, synthetic heterocyclic diamidines have excellent activity against eukaryotic parasites that cause diseases such as… Expand
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Highly Cited
2007
Highly Cited
2007
By enzymatically hydrolyzing the terminal phosphodiester bond at the 3′-ends of DNA breaks, tyrosyl-DNA phosphodiesterase (Tdp1… Expand
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Highly Cited
2006
Highly Cited
2006
A novel trypanocide, 2,5-bis(4-amidinophenyl)furan (DB75), in its prodrug amidoxime-derivative form, 2,5-bis(4-amidinophenyl… Expand
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2004
2004
The current epidemic of sleeping sickness, also known as human African trypanosomiasis in sub-Saharan Africa places nearly 60… Expand
2004
2004
DB75 (2,5-bis(4-amidinophenyl)furan) is a promising antimicrobial agent against African trypanosomiasis and Pneumocystis carinii… Expand
Highly Cited
2003
Highly Cited
2003
6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile (4a… Expand
Highly Cited
1995
Highly Cited
1995
Seven dicationic 2,5-diarylfurans have been synthesized, and their interactions with poly(dA-dT) and the duplex oligomer d… Expand
Highly Cited
1977
Highly Cited
1977
Eighteen substituted 2,5-bis(4-guanylphenyl)furans and related analogues, including "masked" amidines in which the guanyl… Expand