Skip to search formSkip to main contentSkip to account menu

furamidine

Known as: 2,5-BAPF, 2,5-bis(4-amidinophenyl)furan, 2,5-bis(4-guanylphenyl)furan 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AmidinesBenzamidines

Narrower (1)

DB75

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Transport of Dicationic Drugs Pentamidine and Furamidine by Human Organic Cation Transporters
The antiparasitic activity of aromatic diamidine drugs, pentamidine and furamidine, depends on their entry into the pathogenic… 
Review
2008
Review
2008
Antiparasitic compounds that target DNA.
Highly Cited
2008
Highly Cited
2008
Efficacy of the diamidine DB75 and its prodrug DB289, against murine models of human African trypanosomiasis.
Highly Cited
2008
Highly Cited
2008
Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.
Highly Cited
2007
Highly Cited
2007
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1
By enzymatically hydrolyzing the terminal phosphodiester bond at the 3′-ends of DNA breaks, tyrosyl-DNA phosphodiesterase (Tdp1… 
Highly Cited
2006
Highly Cited
2006
Roles for the Trypanosoma brucei P2 Transporter in DB75 Uptake and Resistance
A novel trypanocide, 2,5-bis(4-amidinophenyl)furan (DB75), in its prodrug amidoxime-derivative form, 2,5-bis(4-amidinophenyl… 
Highly Cited
2004
Highly Cited
2004
Characterization of a novel DNA minor-groove complex.
Highly Cited
2003
Highly Cited
2003
Synthesis and antiprotozoal activity of aza-analogues of furamidine.
6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile (4a… 
Highly Cited
1995
Highly Cited
1995
Dicationic diarylfurans as anti-Pneumocystis carinii agents.
Seven dicationic 2,5-diarylfurans have been synthesized, and their interactions with poly(dA-dT) and the duplex oligomer d… 
Highly Cited
1977
Highly Cited
1977
Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)furans.
Eighteen substituted 2,5-bis(4-guanylphenyl)furans and related analogues, including "masked" amidines in which the guanyl… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)