FAQ

furamidine

Known as: 2,5-BAPF, 2,5-bis(4-amidinophenyl)furan, 2,5-bis(4-guanylphenyl)furan 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2017
024619772017

Related topics

Related topics

3 relations

Broader (2)

AmidinesBenzamidines

Narrower (1)

DB75

Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
furamidine
Amidines
Benzamidines
DB75

Papers overview

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2011
2011
Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns.
Current therapies for human African trypanosomiasis (HAT) are unsatisfactory and under threat from emerging drug resistance… (More)
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2009
2009
Transport of dicationic drugs pentamidine and furamidine by human organic cation transporters.
The antiparasitic activity of aromatic diamidine drugs, pentamidine and furamidine, depends on their entry into the pathogenic… (More)
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2008
2008
The mitochondrion is a site of trypanocidal action of the aromatic diamidine DB75 in bloodstream forms of Trypanosoma brucei.
Human African trypanosomiasis (HAT) is a fatal tropical disease caused by infection with protozoans of the species Trypanosoma… (More)
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2006
2006
Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo.
OBJECTIVES Aromatic diamidines have been successfully used to combat a wide range of parasites that cause important human… (More)
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2004
2004
Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis.
Furamidine (DB75) and related unfused aromatic diamidines have proven useful for the treatment of parasitic infections. These… (More)
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2004
2004
Metabolites of an orally active antimicrobial prodrug, 2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime, identified by liquid chromatography/tandem mass spectrometry.
DB75 (2,5-bis(4-amidinophenyl)furan) is a promising antimicrobial agent against African trypanosomiasis and Pneumocystis carinii… (More)
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2003
2003
Synthesis and antiprotozoal activity of aza-analogues of furamidine.
6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile (4a… (More)
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2002
2002
Distribution of furamidine analogues in tumor cells: influence of the number of positive charges.
Fluorescence microscopy has been used to study the cellular distribution properties of a series of DNA binding cationic compounds… (More)
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1995
1995
Dicationic diarylfurans as anti-Pneumocystis carinii agents.
Seven dicationic 2,5-diarylfurans have been synthesized, and their interactions with poly(dA-dT) and the duplex oligomer d… (More)
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1977
1977
Synthesis and antiprotozoal activity of 2,5-bis(4-guanylphenyl)furans.
Eighteen substituted 2,5-bis(4-guanylphenyl)furans and related analogues, including "masked" amidines in which the guanyl… (More)
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