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furamidine

Known as: 2,5-BAPF, 2,5-bis(4-amidinophenyl)furan, 2,5-bis(4-guanylphenyl)furan 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AmidinesBenzamidines

Narrower (1)

DB75

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl‐DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis
The treatment of lupus nephritis is still an unmet medical need requiring new therapeutic approaches. Our group found recently… 
2014
2014
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues.
2009
2009
Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum.
2006
2006
3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity.
Highly Cited
2004
Highly Cited
2004
DB75, a Novel Trypanocidal Agent, Disrupts Mitochondrial Function in Saccharomyces cerevisiae
ABSTRACT The aromatic diamidines represent a class of compounds with broad-spectrum antimicrobial activity; however, their… 
2002
2002
Enhanced Permeability of the Antimicrobial Agent 2,5-Bis(4-Amidinophenyl)Furan Across Caco-2 Cell Monolayers Via Its Methylamidoxime Prodrug
AbstractPurpose. DB75 [2,5-bis(4-amidinophenyl)furan] is a promising antimicrobial agent although it has poor oral potency. In… 
2002
2002
Antimicrobial activity of the DNA minor groove binders furamidine and analogs
Aryl diamidine analogs of pentamidine and berenil that bind to the minor groove of DNA have been developed which show broad… 
2002
2002
Characterizing the fragmentation of 2,5-bis (4-amidinophenyl)furan-bis-O-methylamidoxime and selected metabolites using ion trap mass spectrometry.
A novel prodrug [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime (DB289)] of the promising antimicrobial agent, 2,5-bis(4… 
1999
1999
Inhibition of HIV-1 Tat-TAR interaction by diphenylfuran derivatives: effects of the terminal basic side chains.
1993
1993
Binding of DAPI analogue 2,5-bis(4-amidinophenyl)furan to DNA.
The binding of 2,5-bis(4-amidinophenyl)furan (APF) to calf thymus DNA, [poly(dA-dT)]2, and [poly(dG-dC)]2 has been studied with… 
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