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furamidine

Known as: 2,5-BAPF, 2,5-bis(4-amidinophenyl)furan, 2,5-bis(4-guanylphenyl)furan 
 
National Institutes of Health

Papers overview

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2011
2011
Current therapies for human African trypanosomiasis (HAT) are unsatisfactory and under threat from emerging drug resistance… Expand
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Highly Cited
2009
Highly Cited
2009
The antiparasitic activity of aromatic diamidine drugs, pentamidine and furamidine, depends on their entry into the pathogenic… Expand
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Highly Cited
2009
Highly Cited
2009
African sleeping sickness is a fatal parasitic disease, and all drugs currently in use for treatment have strong liabilities. It… Expand
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Review
2008
Review
2008
Designed, synthetic heterocyclic diamidines have excellent activity against eukaryotic parasites that cause diseases such as… Expand
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Highly Cited
2007
Highly Cited
2007
By enzymatically hydrolyzing the terminal phosphodiester bond at the 3′-ends of DNA breaks, tyrosyl-DNA phosphodiesterase (Tdp1… Expand
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2004
2004
Furamidine (DB75) and related unfused aromatic diamidines have proven useful for the treatment of parasitic infections. These… Expand
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2004
2004
The aromatic diamidines represent a class of compounds with broad-spectrum antimicrobial activity; however, their development is… Expand
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2003
2003
6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile (4a… Expand
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2002
2002
Diphenylfuran diamidines represent an important class of DNA minor groove binders of high therapeutic interest as antiparasitic… Expand
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2002
2002
Fluorescence microscopy has been used to study the cellular distribution properties of a series of DNA binding cationic compounds… Expand
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