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Benzamidines

Known as: Benzamidines [Chemical/Ingredient] 
Amidines substituted with a benzene group. Benzamidine and its derivatives are known as peptidase inhibitors.
National Institutes of Health

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2-aminobenzamidoxime3,4,5-trihydroxybenzamidoxime3,5-dipentadecyloxybenzamidine hydrochloride4'-amidinophenyl-4-chloroanthranilic acid
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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2017
2017
Ru(ii)-Catalyzed annulation of benzamidines and alkynes by C-H/N-H activation: a facile synthesis of 1-aminoisoquinolines.
An inexpensive Ru(ii) complex catalyzes the oxidative annulation reaction of disubstituted alkynes with benzamidines to provide… 
2013
2013
Ligand-free nano copper oxide catalyzed cyanation of aryl halides and sequential one-pot synthesis of 5-substituted-1H-tetrazoles
Highly Cited
2012
Highly Cited
2012
Copper catalyzed N-arylation of amidines with aryl boronic acids and one-pot synthesis of benzimidazoles by a Chan-Lam-Evans N-arylation and C-H activation/C-N bond forming process.
Mono-N-arylation of benzamidines 1 with aryl boronic acids 2 was effectively achieved in the presence of a catalytic amount of Cu… 
Highly Cited
2001
Highly Cited
2001
Structure-based approach for the discovery of bis-benzamidines as novel inhibitors of matriptase.
Matriptase, a trypsin-like serine protease, which may be involved in tissue remodeling, cancer invasion, and metastasis. Potent… 
1999
1999
Prediction of Complement-Inhibitory Activity of Benzamidines Using Topological and Geometric Parameters
A hierarchical approach to quantitative structure-activity relationship (QSAR) modeling has been used to estimate the complement… 
1997
1997
Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists.
The use of 5,6-bicyclic amidines as arginine surrogates in the design of a novel class of potent platelet glycoprotein IIb-IIIa… 
Review
1992
Review
1992
Interactions of thrombin with benzamidine-based inhibitors.
Trypsin and trypsin-like enzymes cleave C-terminal bonds of the basic amino acids Arg and Lys. Inhibitors of these enzymes have… 
1987
1987
Hepatic microsomal N-demethylation of N-methylbenzamidine. N-dealkylation vs N-oxygenation of amidines.
1983
1983
The N-oxidation of benzamidines in vitro.
  • B. Clement
  • Xenobiotica; the fate of foreign compounds in…
  • 1983
  • Corpus ID: 37454032
The enzymic N-oxidation of a series of N-unsubstituted basic benzamidines (I) to a new type of metabolite, the amidoximes (II… 
1978
1978
Inhibition of four human serine proteases by substituted benzamidines.
A series of substituted benzamidines has been examined for their inhibitory activity against the human serine proteases--trypsin… 
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