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3,4,5-trihydroxybenzamidoxime

Known as: trimidox 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Gallic acid (GA) is a naturally occurring polyhydroxyphenolic compound and an excellent free radical scavenger. In this study, we… 
Highly Cited
2004
Highly Cited
2004
Resistance to cytotoxic nucleoside analogues is a major problem in cancer treatment. The cellular mechanisms involved in this… 
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Highly Cited
2003
Highly Cited
2003
Objective: To determine the role of oxidative stress in mediating HIV dementia and to identify novel therapeutic compounds that… 
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2003
2003
PurposeTemozolomide (TMZ), an oral alkylating agent with good penetration of the blood-brain barrier, has shown efficacy in the… 
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2000
2000
Trimidox (3,4,5-trihydroxybenzohydroxamidoxime), a recently synthesized inhibitor of ribonucleotide reductase (RR), was shown to… 
2000
2000
Upon appropriate drug treatment, the human erythroleukemic K562 cells have been shown to produce hemoglobin and F‐cells. Fetal… 
1999
1999
Inhibitors of the cellular enzyme ribonucleotide reductase (hydroxyurea, [HU]) have been proposed as a new therapeutic strategy… 
1997
1997
The DNA-protective activity of hydroxyurea (HU) and novel ribonucleotide reductase (RR) inhibitors amidox (AX), didox (DX) and… 
1995
1995
Ribonucleotide reductase is the rate limiting enzyme of deoxynucleoside triphosphate synthesis and is considered to be an… 
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1994
1994
Increased ribonucleotide reductase (RR) activity has been linked with malignant transformation and tumor cell growth. Therefore… 
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