fropenem

Known as: (+)-(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-hydroxyethylpenem-3-carboxylate, FAROPENEM 
A penem with a tetrahydrofuran substituent at position C2, with broad-spectrum antibacterial activity against many gram-positive and gram-negative… (More)
National Institutes of Health

Papers overview

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2015
2015
An effective regimen for treatment of tuberculosis (TB) is comprised of multiple drugs that inhibit a range of essential cellular… (More)
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2007
2007
Surveillance studies conducted in the United States over the last decade have revealed increasing resistance among community… (More)
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2006
2006
A total of 621 clinical isolates of Haemophilus influenzae collected in Japan between 1995 and 2003 were studied for their… (More)
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Review
2006
Review
2006
The antimicrobial class of penems has the potential to address most of the relevant resistance issues associated with beta-lactam… (More)
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Review
2005
Review
2005
The development and introduction of new antibiotics has, unfortunately, not kept pace with the development of bacterial… (More)
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2004
2004
Escherichia coli accounted for about 80% of organisms in uncomplicated urinary tract infections (UTIs), followed by… (More)
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Highly Cited
2002
Highly Cited
2002
The stability of antipseudomonal beta-lactams in concentrated solutions was examined in view of their potential administration by… (More)
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2002
2002
In this study, we evaluated the current effectiveness of 11 beta-lactam antibiotics for treatment of orofacial odontogenic… (More)
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2001
2001
Pseudomonas aeruginosa exhibits high intrinsic resistance to penem antibiotics such as faropenem, ritipenem, AMA3176, sulopenem… (More)
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Highly Cited
2000
Highly Cited
2000
Organic anions are secreted into urine via organic anion transporters across the renal basolateral and apical membranes. However… (More)
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