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fropenem

Known as: (+)-(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-hydroxyethylpenem-3-carboxylate, FAROPENEM 
A penem with a tetrahydrofuran substituent at position C2, with broad-spectrum antibacterial activity against many gram-positive and gram-negative… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
ABSTRACT An effective regimen for treatment of tuberculosis (TB) is comprised of multiple drugs that inhibit a range of essential… Expand
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2014
2014
ABSTRACT Recent clinical studies indicate that meropenem, a β-lactam antibiotic, is a promising candidate for therapy of drug… Expand
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2013
2013
ABSTRACT Beta-lactams, in combination with beta-lactamase inhibitors, are reported to have activity against Mycobacterium… Expand
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2010
2010
Olmesartan medoxomil (OM) is a prodrug type angiotensin II type 1 receptor antagonist widely prescribed as an antihypertensive… Expand
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Highly Cited
2007
Highly Cited
2007
ABSTRACT Surveillance studies conducted in the United States over the last decade have revealed increasing resistance among… Expand
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2006
2006
OBJECTIVES The aim of the present study was to determine correlation between bmeB efflux pump overexpression and resistance to… Expand
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Highly Cited
2002
Highly Cited
2002
ABSTRACT The stability of antipseudomonal β-lactams in concentrated solutions was examined in view of their potential… Expand
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Highly Cited
2002
Highly Cited
2002
In this study, we evaluated the current effectiveness of 11 beta-lactam antibiotics for treatment of orofacial odontogenic… Expand
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Highly Cited
2001
Highly Cited
2001
ABSTRACT Pseudomonas aeruginosa exhibits high intrinsic resistance to penem antibiotics such as faropenem, ritipenem, AMA3176… Expand
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Highly Cited
2000
Highly Cited
2000
Organic anions are secreted into urine via organic anion transporters across the renal basolateral and apical membranes. However… Expand
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