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flaviolin

National Institutes of Health

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Naphthoquinones

Papers overview

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2019
2019
Identification of novel cytochrome P450 monooxygenases from actinomycetes capable of intermolecular oxidative C-C coupling reactions.
2014
2014
Characterization of microorganisms isolated from the black dirt of toilet bowls and componential analysis of the black dirt.
We have previously conducted a microflora analysis and examined the biofilm-forming activity of bacteria isolated from toilet… 
2008
2008
Identification of a cryptic type III polyketide synthase (1,3,6,8-tetrahydroxynaphthalene synthase) from Streptomyces peucetius ATCC 27952.
2007
2007
Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.
Cytochrome P450 158A2 (CYP158A2) has been shown to catalyze an unusual oxidative C-C coupling reaction to polymerize flaviolin… 
2007
2007
Understanding the substrate selectivity and the product regioselectivity of Orf2-catalyzed aromatic prenylations.
Orf2, a recently identified prenyltransferase of aromatic natural products, displays relaxed substrate selectivity and… 
2006
2006
Chip‐Based Polyketide Biosynthesis and Functionalization
We demonstrate construction and novel compound synthesis from a synthetic metabolic pathway consisting of a type III polyketide… 
Highly Cited
2005
Highly Cited
2005
Role of Active Site Water Molecules and Substrate Hydroxyl Groups in Oxygen Activation by Cytochrome P450 158A2
From the x-ray crystal structure of CYP158A2 (Zhao, B., Guengerich, F. P., Bellamine, A., Lamb, D. C., Izumikawa, M., Lei, L… 
2005
2005
Exploiting the reaction flexibility of a type III polyketide synthase through in vitro pathway manipulation.
A synthetic metabolic pathway has been constructed in vitro consisting of the type III polyketide synthase from Streptomyces… 
1976
1976
Isolation of Flaviolin from the Potato Culture Solution of Phoma wasabiae Yokogi
Flaviolin was found in the blackish potato culture solution of Phoma wasabiae 
1975
1975
Biosynthesis of flaviolin and 5,8-dihydroxy-2,7-dimethoxy-1,4-naphthoquinone.
Tracer experiments indicate a polyketide origin for the production of flaviolin (2,5,7-trihydroxy-1,4-naphthoquinone) by… 
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