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fibroblast growth factor receptor 4
Known as:
Receptor, Fibroblast Growth Factor, Type 4
, Fibroblast Growth Factor Receptors 4
, Receptor, Fibroblast Growth Factor, Type 4 [Chemical/Ingredient]
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A fibroblast growth factor receptor that is mainly expressed in LUNG; KIDNEY; PANCREAS; and SPLEEN. It also plays an important role in SKELETAL…
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National Institutes of Health
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Related topics
Related topics
12 relations
FGFR4 gene
FGFR4 wt Allele
In Blood
Process of secretion
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Narrower (2)
FGFR4 protein, Coturnix coturnix
FGFR4 protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
2-Aminopyrimidine Derivatives as New Selective Fibroblast Growth Factor Receptor 4 (FGFR4) Inhibitors.
Cheng Mo
,
Zhang Zhang
,
+9 authors
Ke Ding
ACS Medicinal Chemistry Letters
2017
Corpus ID: 31033711
A series of 2-aminopyrimidine derivatives were designed and synthesized as highly selective FGFR4 inhibitors. One of the most…
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2015
2015
Abstract 2488: FGFR4 as a potential therapeutic target for monoclonal antibody based intervention in rhabdomyosarcoma
S. Baskar
,
Nityashree Shivaprasad
,
+8 authors
J. Khan
2015
Corpus ID: 70870047
Background: Rhabdomyosarcoma (RMS) is most common soft tissue sarcoma in childhood and adolescence. There are two major subtypes…
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2014
2014
Structural analysis of the human Fibroblast Growth Factor Receptor 4 kinase - Expression and purification of the human calcium channel ORAI1
E. Lesca
2014
Corpus ID: 90151449
In this thesis I show crystal structures of the FGFR4 kinase. Two apo-structures have been solved in different crystal forms, and…
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2012
2012
Fibroblast growth factor receptor 4 polymorphisms are associated with coronary artery disease.
Hao Chen
,
Jiabin Tong
,
+5 authors
Changsheng Ma
Genetic Testing and Molecular Biomarkers
2012
Corpus ID: 34946743
Fibroblast growth factor receptor 4 (FGFR4) plays crucial roles in vascular smooth muscle cell proliferation and atherosclerosis…
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2011
2011
Sulfated Glycosaminoglycans Are Required for Specific and Sensitive Fibroblast Growth Factor (FGF) 19 Signaling via FGF Receptor 4 and betaKlotho*
Masao Nakamura
,
Y. Uehara
,
+5 authors
T. Imamura
Journal of Biological Chemistry
2011
Corpus ID: 10949549
Secreted from intestine, human fibroblast growth factor 19 (hFGF19) is an endocrine metabolic regulator that controls bile acid…
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2011
2011
The Role of Acidic Fibroblast Growth Factor and Fibroblast Growth Factor Receptor 4 in High Grade Serous Carcinoma
T. Zaid
2011
Corpus ID: 56383230
Background: High grade serous carcinoma (HGSC) whether ovarian, tubal or primary peritoneal, continues to be the most lethal…
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2010
2010
Metabolic Regulator Klotho Interacts with Fibroblast Growth Factor Receptor 4 (FGFR4) to Induce Apoptosis and
Yongde Luo
,
Chaofeng Yang
,
+5 authors
W. Mckeehan
2010
Corpus ID: 263543767
Inorgansinvolvedinmetabolichomeostasis,transmembrane and klothos direct FGFR signaling to control of metabolicpathways…
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2005
2005
Generation and characterization of a panel of monoclonal antibodies specific for human fibroblast growth factor receptor 4 (FGFR4).
Chaoyuan Chen
,
Sima Patel
,
+7 authors
D. Soltis
Hybridoma
2005
Corpus ID: 12225855
Fibroblast growth factor receptor 4 (FGFR4) is a member of the FGFR family of receptor tyrosine kinases, and plays important…
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2000
2000
An overexpression of fibroblast growth factor (FGF) and FGF receptor 4 in a severe clinical phenotype of facioscapulohumeral muscular dystrophy
A. Saito
,
I. Higuchi
,
+8 authors
M. Osame
Muscle and Nerve
2000
Corpus ID: 29255581
We evaluated the expression of a select panel of growth factors and their receptors, including fibroblast growth factor 1 (FGF‐1…
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1998
1998
Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally.
D. Olson
,
C. Deng
,
D. Hanahan
Cell growth & differentiation : the molecular…
1998
Corpus ID: 10133875
Fibroblast growth factor receptor 4 (FGFR4) gene expression is activated in late-stage beta-cell tumors that develop in…
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