Skip to search formSkip to main contentSkip to account menu

fibroblast growth factor receptor 4

Known as: Receptor, Fibroblast Growth Factor, Type 4, Fibroblast Growth Factor Receptors 4, Receptor, Fibroblast Growth Factor, Type 4 [Chemical/Ingredient] 
A fibroblast growth factor receptor that is mainly expressed in LUNG; KIDNEY; PANCREAS; and SPLEEN. It also plays an important role in SKELETAL… 
National Institutes of Health

Related topics

Related topics

12 relations
FGFR4 geneFGFR4 wt AlleleIn BloodProcess of secretion

Narrower (2)

FGFR4 protein, Coturnix coturnixFGFR4 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
2-Aminopyrimidine Derivatives as New Selective Fibroblast Growth Factor Receptor 4 (FGFR4) Inhibitors.
A series of 2-aminopyrimidine derivatives were designed and synthesized as highly selective FGFR4 inhibitors. One of the most… 
2015
2015
Abstract 2488: FGFR4 as a potential therapeutic target for monoclonal antibody based intervention in rhabdomyosarcoma
Background: Rhabdomyosarcoma (RMS) is most common soft tissue sarcoma in childhood and adolescence. There are two major subtypes… 
2014
2014
Structural analysis of the human Fibroblast Growth Factor Receptor 4 kinase - Expression and purification of the human calcium channel ORAI1
In this thesis I show crystal structures of the FGFR4 kinase. Two apo-structures have been solved in different crystal forms, and… 
2012
2012
Fibroblast growth factor receptor 4 polymorphisms are associated with coronary artery disease.
Fibroblast growth factor receptor 4 (FGFR4) plays crucial roles in vascular smooth muscle cell proliferation and atherosclerosis… 
2011
2011
Sulfated Glycosaminoglycans Are Required for Specific and Sensitive Fibroblast Growth Factor (FGF) 19 Signaling via FGF Receptor 4 and betaKlotho*
Secreted from intestine, human fibroblast growth factor 19 (hFGF19) is an endocrine metabolic regulator that controls bile acid… 
2011
2011
The Role of Acidic Fibroblast Growth Factor and Fibroblast Growth Factor Receptor 4 in High Grade Serous Carcinoma
Background: High grade serous carcinoma (HGSC) whether ovarian, tubal or primary peritoneal, continues to be the most lethal… 
2010
2010
Metabolic Regulator Klotho Interacts with Fibroblast Growth Factor Receptor 4 (FGFR4) to Induce Apoptosis and
Inorgansinvolvedinmetabolichomeostasis,transmembrane and klothos direct FGFR signaling to control of metabolicpathways… 
2005
2005
Generation and characterization of a panel of monoclonal antibodies specific for human fibroblast growth factor receptor 4 (FGFR4).
Fibroblast growth factor receptor 4 (FGFR4) is a member of the FGFR family of receptor tyrosine kinases, and plays important… 
2000
2000
An overexpression of fibroblast growth factor (FGF) and FGF receptor 4 in a severe clinical phenotype of facioscapulohumeral muscular dystrophy
We evaluated the expression of a select panel of growth factors and their receptors, including fibroblast growth factor 1 (FGF‐1… 
1998
1998
Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally.
Fibroblast growth factor receptor 4 (FGFR4) gene expression is activated in late-stage beta-cell tumors that develop in… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)