Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

fenclozic acid

Known as: 2-(4-chlorophenyl)-4--thiazoleacetic acid 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The metabolic fate of the human hepatotoxin fenclozic acid ([2-(4-chlorophenyl)-1,3-thiazol-4-yl]acetic acid) (Myalex) was… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
2016
2016
The distribution, metabolism, excretion and hepatic effects of the human hepatotoxin fenclozic acid were investigated following… Expand
  • figure 1
  • table 2
  • figure 2
  • table 1
  • figure 3
2014
2014
Abstract 1. The distribution, metabolism, excretion and hepatic effects of fenclozic acid were investigated following a single… Expand
2014
2014
Fenclozic acid (Myalex) was developed by ICI pharmaceuticals in the 1960s for the treatment of rheumatoid arthritis and was a… Expand
2013
2013
The carboxylic acid NSAID fenclozic acid exhibited an excellent preclinical safety profile and promising clinical efficacy, yet… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
1981
1981
1. The metabolic fate of [14C]fenclozic acid (ICI 54450) in rat was determined after intraduodenal administration at different… Expand
1979
1979
Fenclozic acid, a prostaglandin synthesis inhibitor, was administered to male rats by stomach intubation. A second group of rats… Expand
1971
1971
  • D. Platt
  • Journal of pharmaceutical sciences
  • 1971
  • Corpus ID: 45693524
The pharmacokinetic properties of the anti-inflammatory agent, fenclozic acid, have been established in the dog, calf, sheep, and… Expand
1969
1969
  • B. Newbould
  • British journal of pharmacology
  • 1969
  • Corpus ID: 44400499
1 Fenclozic acid (2‐(4‐chlorophenyl)thiazol‐4‐ylacetic acid; I.C.I. 54, 450; “Myalex”) is one representative of a new class of… Expand
1969
1969
Fenclozic acid (I.C.I. 54,450; 2-(p-chlorophenyl) thiazol-4-ylacetic acid; Myalex*) (Hepworth, Newbould, Platt, and Stacey, 1969… Expand