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fatty-acid synthase activity

Known as: acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing), lovastatin nonaketide synthase activity, acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing) 
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9… 
National Institutes of Health

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Fatty-acid synthase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Combination of fish oil and fish protein hydrolysate reduces the plasma cholesterol level with a concurrent increase in hepatic cholesterol level in high-fat-fed Wistar rats.
2009
2009
A Simplified Scintillation Proximity Assay for Fatty Acid Synthase Activity: Development and Comparison with Other FAS Activity Assays
Fatty acid synthase (FAS), an essential enzyme for de novo lipogenesis, has been implicated in a number of disease states… 
Highly Cited
2007
Highly Cited
2007
Specificity of acyl transfer from 2-mercaptobenzamide thioesters to the HIV-1 nucleocapsid protein.
The HIV-1 nucleocapsid protein (NCp7) is a small, highly conserved protein with two zinc-binding domains that are essential for… 
2003
2003
Characterization of fatty acid synthase activity using scintillation proximity.
FAS is a 544-kDa dimeric enzyme consisting of seven functional catalytic components that synthesize long-chain fatty acids from… 
2000
2000
Acetyl-CoA carboxylase and fatty acid synthase activity and immunodetectable protein in adipose tissues of ruminants: effect of temperature and feeding level.
To gain insights into the regulation of fat synthesis, we have investigated the effect of cold environmental exposure and feed… 
Highly Cited
1999
Highly Cited
1999
Catalytic enantioselective Michael additions to unsaturated ester derivatives using chiral copper(II) Lewis acid complexes.
[formula: see text] Chiral Cu(II) bisoxazoline (box) Lewis acids have been developed as catalysts of the Michael addition of… 
1992
1992
Pre‐translational regulation by glucocorticoid of fatty acid and phosphatidylcholine synthesis in type II cells from fetal rat lung
1989
1989
Rates of lipogenesis in fetal hepatocytes in suspension and in primary culture: hormonal effects.
Review
1986
Review
1986
Regulation of the gene for fatty acid synthase.
The activity of hepatic fatty acid synthase (EC 2.3.1.85) correlates positively with the rate of synthesis of long-chain fatty… 
1986
1986
Chain-shortening of a xenobiotic acyl compound by the peroxisomal beta-oxidation system in rat liver.
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