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Monitoring of phthalic acid monoesters in river water by solid-phase extraction and GC-MS determination.
An analytical method for monitoring 10 phthalic acid monoesters in river water was investigated by solid-phase extraction, methylation with diazomethane, and GC-MS, in which PS-2 gave the highest recoveries of the three solid phases. Expand
Changes in CoA pools in hepatic peroxisomes of the rat under various conditions.
The results obtained from these experiments indicate that the peroxisomal beta-oxidation system is controlled not only at the enzyme level but also at the substrate or co-factor level. Expand
Long-chain acyl-CoA hydrolase from rat brain cytosol: purification, characterization, and immunohistochemical localization.
Brain cytosols prepared from ten mammalian species including human contained a single polypeptide reactive to anti-ACH antibody with molecular masses of 34-36 kDa, together with high activities of palmitoyl-CoA hydrolase, suggesting the physiological significance of ACH in the brain, although its precise role remains to be determined. Expand
Efficacy of orally administered superfine dispersed lentinan (beta-1,3-glucan) for the treatment of advanced colorectal cancer.
SD was safe and effective for suppressing the adverse effects of chemotherapy as well as improving QOL, and the binding ability of PBM to LNT appears to be a promising predictor of QOL improvement after SDL administration. Expand
Purification and properties of long-chain acyl-CoA hydrolases from the liver cytosol of rats treated with peroxisome proliferator.
Examination with various reagents including divalent cations, sulfhydryl-blocking reagent, nucleotides, and hypolipidemic drugs characterized ACH1 and ACH2 with several properties distinct from those of mitochondrial and microsomal hydrolases, and suggested the presence of the enzymes also in extrahepatic tissues. Expand
Intratesticular localization of the organic solute carrier protein, OSCP1, in spermatogenic cells in mice
Results suggest that mouse testis OSCP1 may indirectly mediate substrate uptake into meiotic and spermiogenic germ cells, within the cytosol. Expand
Studies on peroxisomes. I. Intraparticulate localization of peroxisomal enzymes in rat liver.
Results support the view that catalase exists in the matrix of the peroxisomes and urate oxidase in the core of rat liver homogenate and find that tightness of binding of the four enzymes studied to heavy sedimentable material increased in the order. Expand
A new colorimetric determination of D-amino acid oxidase and urate oxidase activity.
The method can be useful as a method of activity determination for studying enzyme kinetics and the reaction mechanism and showed good reproducibility and accuracy. Expand
cDNA cloning and genomic organization of peroxisome proliferator-inducible long-chain acyl-CoA hydrolase from rat liver cytosol.
The cDNA for a peroxisome proliferator-inducible long-chain acyl-CoA hydrolase from rat liver cytosol, referred to as rLACH2, was isolated and its genomic structure was determined. The cDNA encoded aExpand
Hepatocarcinogenesis by peroxisome proliferators.
  • T. Suga
  • Biology, Medicine
  • The Journal of toxicological sciences
  • 1 February 2004
Findings may indicate that decreases in hepatic HGF levels are specific events induced by peroxisome proliferators but not by genotoxic carcinogenesis, and that those changes play an important role in the promotion of neoplastic or preneoplastic cell growth induced by each of these drugs. Expand