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fascaplysine

Known as: fascaplisine, fascaplysin 
National Institutes of Health

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Indoles

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2016
2016
Combination screening in vitro identifies synergistically acting KP372-1 and cytarabine against acute myeloid leukemia.
2015
2015
Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma
Despite recent advances in targeted therapies and immunotherapies metastatic melanoma remains only rarely curable. The objective… 
2015
2015
Copper-Catalyzed Hydroarylation of Alkynes for the Synthesis of Fascaplysin, Rutacarpine and Granulatimide Analogues
Abstract An efficient copper-catalyzed π-activation protocol has been developed for the intramolecular hydroarylation of alkynes… 
2011
2011
3-bromohomofascaplysin A, a fascaplysin analogue from a Fijian Didemnum sp. ascidian.
2010
2010
Effect of Marine Bioactive Alkaloid Fascaplysin on Metabolites of Hepatocellular Carcinoma Cell Line Bel-7402
OBJECTIVE To study the effect of marine bioactive alkaloid fascaplysin on metabolites of hepatocellular carcinoma cell line BeL… 
2009
2009
[Anti-proliferation of human cervical cancer HeLa cell line by fascaplysin through apoptosis induction].
This study is to investigate the effect of fascaplysin on human cervical cancer cells (HeLa) in order to provide insights into… 
2008
2008
Study Advances on Synthesis and Structural-activity Relationship of Marine Bioactive Compound Fascaplysin and Its Derivatives
Fascaplysin is a kind of indole alkaloid which can inhibit the proliferation of tomour cells.Fascaplysin is discovered from… 
2006
2006
Regioselective photo-oxidation of 1-benzyl-4,9-dihydro-3H-beta-carbolines.
The synthesis of a series of beta-carboline-based analogues of the natural product fascaplysin is presented; the compounds were… 
2006
2006
Inhibition of cancer cell growth by cyclin dependent kinase 4 inhibitors synthesized based on the structure of fascaplysin.
2004
2004
The fate of pancreatic tumor cell lines following p16 overexpression depends on the modulation of CDK2 activity
AbstractRestitution of lost tumor-suppressor activities may be a promising strategy to target specifically cancer cells. However… 
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