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falipamil

Known as: 1H-Isoindol-1-one, 2-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-2,3-dihydro-5,6-dimethoxy-, 5,6-dimethoxy-2-(3-((alpha-(3,4-dimethoxy)phenylethyl)methylamino)propyl)phthalimidine, AQ-A39 
National Institutes of Health

Related topics

Related topics

8 relations

Narrower (3)

AQ-A 39AQA 39Clfalipamil hydrochloride

Broader (5)

Anti-Arrhythmia AgentsCalcium Channel BlockersCardiovascular AgentsParasympatholytics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Discovery of 3-n-butyl-2,3-dihydro-1H-isoindol-1-one as a potential anti-ischemic stroke agent
To develop novel anti-ischemic stroke agents with better therapeutic efficacy and bioavailability, we designed and synthesized a… 
2008
2008
[(18)F]-labeled isoindol-1-one and isoindol-1,3-dione derivatives as potential PET imaging agents for detection of beta-amyloid fibrils.
Highly Cited
1990
Highly Cited
1990
Specific bradycardic agents. 1. Chemistry, pharmacology, and structure-activity relationships of substituted benzazepinones, a-new class of compounds exerting antiischemic properties.
Structural modification of the calcium-antagonist verapamil (1) by replacement of the lipophilic alpha-isopropylacetonitrile… 
1989
1989
Effects of Falipamil (AQ‐A 39) on Heart Rate and Blood Pressure in Resting and Exercising Healthy Volunteers
Falipamil (AQ-A 39) is a new verapamil derivative which exerts antitachycardic effects by a direct action on the sinus node. Its… 
1988
1988
Bradycardic effects of AQ-A 39 (falipamil) in situ and in isolated, blood-perfused dog hearts. Comparison with alinidine and verapamil.
The cardiovascular effects of a specific bradycardic agent, AQ-A 39, were investigated in intact donor dogs and isolated and… 
1988
1988
Characterization of guinea-pig cardiac muscarinic receptors by radioligand dissociation kinetics.
1987
1987
Pharmacological influence of specific bradycardic agents on the pacemaker current of sheep cardiac Purkinje fibres. A comparison between three different molecules.
The diastolic depolarization rate of isolated sheep Purkinje fibres was reduced in the presence of micromolar concentrations of… 
Review
1987
Review
1987
Specific bradycardic agents--a novel pharmacological class?
Data have been reviewed and presented which suggest that substances from two different chemical groups, congeners of alinidine… 
1987
1987
Clinical pharmacology of two specific bradycardiac agents.
The effect of two i.v.-infusion regimens of falipamil on atropine-induced changes of heart rate and the effect of ULFS 49 Cl in 3… 
1986
1986
Beneficial effects of two specific bradycardic agents AQ-A39 (falipamil) and AQ-AH 208 on reversible myocardial reperfusion damage in anesthetized dogs.
The effects of 2 specific bradycardic agents, AQ-A39 [5,6-dimethoxy-2-[3-([alpha-(3,4-dimethoxy)phenylethyl]methyl-amino) propyl… 
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