extrathymic T cell selection
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Supernumerary parathyroid glands (SPGs) are found in 13% of random autopsies. The high incidence of SPGs could explain the… Expand The development of a broad repertoire of T cells, which is essential for effective immune function, occurs in the thymus… Expand IL-6 is a proinflammatory cytokine and its overproduction is implicated in a variety of inflammatory disorders. Recent in vitro… Expand The extract of licorice (Glycyrrhiza glabra L.) has been widely used for many centuries in the traditional Chinese medicine as… Expand Little is known about the ontogeny of naturally occurring CD4(+)CD25(+) regulatory/suppressor T cells that play a major role in… Expand IL-7-deficient (IL-7 ) mice have reduced numbers of B and TCRab cells, but lack mature TCRgd cells. Although most T cell… Expand The majority of T cells located in peripheral blood, spleen and lymph nodes are dependent on the thymus for proper… Expand The immunophysiology of pregnancy was investigated in relation to how extra- and intrathymic pathways of T cell differentiation… Expand Self-reactive T lymphocytes escaping thymic tolerance induction can be rendered non-responsive by contact with antigens in the… Expand Three hundred and eighty-two patients undergoing thymectomy for myasthenia gravis at 4 London hospitals during the years 1942-64… Expand