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ex vivo-expanded HER2-specific T cells

Known as: HER2 Specific T-Cells 
T cells specific for the human epidermal growth factor receptor 2 (HER2) with potential immunopotentiating activity. T cells directed against HER2… 
National Institutes of Health

Related topics

Related topics

4 relations
Antigen SensitizationCytotoxic T-LymphocytesT-Cell Activationimmunopotentiation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Visualization of HER2-specific breast cancer intratumoral heterogeneity using 64Cu-DOTA-trastuzumab PET
Evaluation of human epidermal growth factor receptor 2 (HER2) expression in tumor tissues using immunohistochemistry (IHC) or in… 
2017
2017
Cytotoxicity of targeted HER2-specific phototoxins based on flavoprotein miniSOG is determined by the rate of their internalization
The concept of targeted therapy implies the development of bifunctional agents complementing the therapeutic module with a… 
2016
2016
HER2-specific DARPin-Liposomes: fabrication and characterization
2013
2013
HER2-specific aptide conjugated magneto-nanoclusters for potential breast cancer imaging and therapy.
Here, we report a nanotheranostic system that enables simultaneous imaging and therapy of HER2-overexpressing tumors. We first… 
Highly Cited
2011
Highly Cited
2011
Hyperthermia-triggered intracellular delivery of anticancer agent to HER2(+) cells by HER2-specific affibody (ZHER2-GS-Cys)-conjugated thermosensitive liposomes (HER2(+) affisomes).
2010
2010
Application of NIR fluorescent markers to quantify expression level of HER2 receptors in carcinomas in vivo
HER2 overexpression has been associated with a poor prognosis and resistance to therapy in breast cancer patients. However… 
2009
2009
Design, synthesis and biological evaluation of a multifunctional HER2-specific Affibody molecule for molecular imaging
PurposeThe purpose of this study was to design and evaluate a novel platform for labelling of Affibody molecules, enabling both… 
Highly Cited
2007
Highly Cited
2007
99mTc-chelator engineering to improve tumour targeting properties of a HER2-specific Affibody molecule
PurposeMonitoring HER2 expression is crucial for selection of breast cancer patients amenable to HER2-targeting therapy. The… 
Highly Cited
2006
Highly Cited
2006
HER2-Specific T-Cell Immune Responses in Patients Vaccinated with Truncated HER2 Protein Complexed with Nanogels of Cholesteryl Pullulan
Purpose: We developed a complex of tumor antigen protein with a novel nanoparticle antigen delivery system of cholesteryl… 
Highly Cited
2001
Highly Cited
2001
The Generation of Both T Killer and Th Cell Clones Specific for the Tumor-Associated Antigen HER2 Using Retrovirally Transduced Dendritic Cells1
Induction of antitumor immunity involves the presence of both CD8+ CTLs and CD4+ Th cells specific for tumor-associated Ags… 
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