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esorubicin

Known as: 4-desoxydoxorubicin, Deoxydoxorubicin, 4'-Deoxyadriamycin 
A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential antineoplastic activity. Esorubicin intercalates… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Antibiotics, AntineoplasticDoxorubicin

Narrower (1)

IMI 58
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1991
1991
Interaction between second generation anthracyclines and DNA in the nucleosomal structure.
The interaction between three anthracycline antibiotics of second generation (9-deoxydoxorubicin, 9-DAM, 4-demethoxydaunorubicin… 
Highly Cited
1989
Highly Cited
1989
Comparative cytotoxicity, DNA synthesis inhibition and drug incorporation of eight anthracyclines in a model of doxorubicin-sensitive and -resistant rat glioblastoma cells.
1987
1987
Metabolism of adriamycin in hepatocytes isolated from the rat and the rabbit.
Highly Cited
1986
Highly Cited
1986
Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo.
The mechanisms of the resistance of intestinal cancer to anthracyclines were studied on an experimental model of rat colon cancer… 
1986
1986
Anthracycline binding to synthetic and natural membranes. A study using resonance energy transfer.
The binding of adriamycin and its two analogues 4'-epidoxorubicin and 4'-deoxydoxorubicin to synthetic and mitochondrial… 
1985
1985
Method for the determination of 4'-deoxydoxorubicin, 4'-deoxydoxorubicinol and their 7-deoxyaglycones in human serum by high-performance liquid chromatography.
1984
1984
Phase I trial of esorubicin (4'deoxydoxorubicin).
A phase I study of 4'deoxydoxorubicin (esorubicin) was performed on an every-21-day bolus intravenous (IV) schedule in 36… 
1983
1983
Role of the fast-exchanging calcium compartment in the early cardiotoxicity of anthracycline analogs.
1983
1983
Antitumor activity in mice of 4'-deoxydoxorubicin in comparison with doxorubicin.
1981
1981
Chemotherapy of human colorectal tumor xenografts in athymic mice with clinically active drugs: 5‐fluorouracile and 1‐3‐bis‐(‐2‐chloroethyl)‐1‐nitrosourea (bcnu). Comparison with doxorubicin…
The effects of single‐agent therapy with two clinically useful drugs, 5‐fluorouracil (5‐FU) and 1‐3‐bis‐(2‐chloro‐ethyl)‐1… 
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