esorubicin

Known as: 4-desoxydoxorubicin, Deoxydoxorubicin, 4'-Deoxyadriamycin 
A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential antineoplastic activity. Esorubicin intercalates… (More)
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Antibiotics, AntineoplasticDoxorubicin

Narrower (1)

IMI 58
analogs & derivatives

Papers overview

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2009
2009
ICC-CLASS: isotopically-coded cleavable crosslinking analysis software suite
Successful application of crosslinking combined with mass spectrometry for studying proteins and protein complexes requires… (More)
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2004
2004
Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines.
The antimalarial artemisinins also reveal profound cytotoxic activity against tumor cells. Artemisinins harbor an endoperoxide… (More)
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1992
1992
Cinchonine, a potent efflux inhibitor to circumvent anthracycline resistance in vivo.
Circumvention of multidrug resistance is a new field of investigation in cancer chemotherapy, and safe and potent multidrug… (More)
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Highly Cited
1986
Highly Cited
1986
Derivation and preliminary characterisation of adriamycin resistant lines of human lung cancer cells.
We have produced adriamycin (ADM)-resistant variants of the human lung cancer cell lines NCI-H69 (small cell), MOR… (More)
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1986
1986
Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo.
The mechanisms of the resistance of intestinal cancer to anthracyclines were studied on an experimental model of rat colon cancer… (More)
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Review
1986
Review
1986
Clinical studies with new anthracyclines: epirubicin, idarubicin, esorubicin.
Analogue development is one of the most intensively pursued anticancer drugs research projects. The rationale in anthracycline… (More)
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1984
1984
Phase I trial of esorubicin (4'deoxydoxorubicin).
A phase I study of 4'deoxydoxorubicin (esorubicin) was performed on an every-21-day bolus intravenous (IV) schedule in 36… (More)
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1984
1984
Metabolism of 4'-modified analogs of doxorubicin. unique glucuronidation pathway for 4'-epidoxorubicin.
The metabolism of doxorubicin (A), 4'-epidoxorubicin (E) and 4'-deoxydoxorubicin (D) was studied in vitro by incubating the… (More)
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1984
1984
Symposium on estrogens in the environment, III.
In an experimental setting, 4'-deoxydoxorubicin (4'-deoxy-DX) shows minimal cardiotoxicity as well as the marked antitumoral… (More)
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1984
1984
Self-association of doxorubicin and related compounds in aqueous solution.
The dimerization of doxorubicin, daunorubicin, and their 4-demethoxy, 4'-epi, and 4'-deoxy analogues was studied… (More)
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