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esorubicin
Known as:
4-desoxydoxorubicin
, Deoxydoxorubicin
, 4'-Deoxyadriamycin
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A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential antineoplastic activity. Esorubicin intercalates…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (2)
Antibiotics, Antineoplastic
Doxorubicin
Narrower (1)
IMI 58
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines.
T. Efferth
,
F. Oesch
Biochemical Pharmacology
2004
Corpus ID: 36924750
Highly Cited
1995
Highly Cited
1995
Symposium on estrogens in the environment, III.
J. McLachlan
,
K. Korach
Environmental Health Perspectives
1995
Corpus ID: 1819519
In an experimental setting, 4'-deoxydoxorubicin (4'-deoxy-DX) shows minimal cardiotoxicity as well as the marked antitumoral…
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Highly Cited
1990
Highly Cited
1990
Mechanisms of resistance of confluent human and rat colon cancer cells to anthracyclines: alteration of drug passive diffusion.
H. Pelletier
,
J. Millot
,
B. Chauffert
,
M. Manfait
,
P. Genne
,
F. Martin
Cancer Research
1990
Corpus ID: 15563971
Two colon cancer cell lines, HT-29 (human) and DHD/K12/TRb (rat), were grown as monolayer cultures to various confluence degrees…
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Highly Cited
1986
Highly Cited
1986
Derivation and preliminary characterisation of adriamycin resistant lines of human lung cancer cells.
P. Twentyman
,
N. Fox
,
K. Wright
,
N. Bleehen
British Journal of Cancer
1986
Corpus ID: 13079684
We have produced adriamycin (ADM)-resistant variants of the human lung cancer cell lines NCI-H69 (small cell), MOR…
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Highly Cited
1986
Highly Cited
1986
Comparative intracellular uptake of adriamycin and 4'-deoxydoxorubicin by non-small cell lung tumor cells in culture and its relationship to cell survival.
D. Kerr
,
A. Kerr
,
R. Freshney
,
S. Kaye
Biochemical Pharmacology
1986
Corpus ID: 20187232
Highly Cited
1984
Highly Cited
1984
Self-association of doxorubicin and related compounds in aqueous solution.
M. Menozzi
,
L. Valentini
,
E. Vannini
,
F. Arcamone
Journal of Pharmacy and Science
1984
Corpus ID: 24373795
The dimerization of doxorubicin, daunorubicin, and their 4-demethoxy, 4'-epi, and 4'-deoxy analogues was studied…
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Highly Cited
1984
Highly Cited
1984
Metabolism of 4'-modified analogs of doxorubicin. unique glucuronidation pathway for 4'-epidoxorubicin.
H. Weenen
,
J. van Maanen
,
M. D. de Planque
,
J. Mcvie
,
H. Pinedo
European Journal of Cancer and Clinical Oncology
1984
Corpus ID: 24515845
Highly Cited
1977
Highly Cited
1977
Plasma pharmacokinetics of adriamycin and its metabolites in humans with normal hepatic and renal function.
R. Benjamin
,
C. Riggs
,
N. Bachur
Cancer Research
1977
Corpus ID: 40751262
A new, nondestructive, plasma extraction technique ultilizing chloroform:isopropyl alcohol (1:1) and ammonium sulfate saturation…
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Highly Cited
1976
Highly Cited
1976
Adriamycin metabolism in man. Evidence from urinary metabolites.
S. Takanashi
,
N. Bachur
Drug Metabolism And Disposition
1976
Corpus ID: 1801658
We studied the human metabolism of adriamycin by isolating and identifying urinary metabolites which retain adriamycin's specific…
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Highly Cited
1976
Highly Cited
1976
Synthesis and antitumor activity of 4'-deoxydaunorubicin and 4'-deoxyadriamycin.
F. Arcamone
,
S. Penco
,
S. Redaelli
,
S. Hanessian
Journal of Medicinal Chemistry
1976
Corpus ID: 9690510
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