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esorubicin

Known as: 4-desoxydoxorubicin, Deoxydoxorubicin, 4'-Deoxyadriamycin 
A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential antineoplastic activity. Esorubicin intercalates… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

Antibiotics, AntineoplasticDoxorubicin

Narrower (1)

IMI 58
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1990
Highly Cited
1990
Mechanisms of resistance of confluent human and rat colon cancer cells to anthracyclines: alteration of drug passive diffusion.
Two colon cancer cell lines, HT-29 (human) and DHD/K12/TRb (rat), were grown as monolayer cultures to various confluence degrees… 
Highly Cited
1989
Highly Cited
1989
Comparative cytotoxicity, DNA synthesis inhibition and drug incorporation of eight anthracyclines in a model of doxorubicin-sensitive and -resistant rat glioblastoma cells.
Highly Cited
1986
Highly Cited
1986
Comparative intracellular uptake of adriamycin and 4'-deoxydoxorubicin by non-small cell lung tumor cells in culture and its relationship to cell survival.
Highly Cited
1986
Highly Cited
1986
Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo.
The mechanisms of the resistance of intestinal cancer to anthracyclines were studied on an experimental model of rat colon cancer… 
1986
1986
New anthracycline analogs in advanced breast cancer.
1986
1986
Anthracycline binding to synthetic and natural membranes. A study using resonance energy transfer.
The binding of adriamycin and its two analogues 4'-epidoxorubicin and 4'-deoxydoxorubicin to synthetic and mitochondrial… 
Highly Cited
1984
Highly Cited
1984
Metabolism of 4'-modified analogs of doxorubicin. unique glucuronidation pathway for 4'-epidoxorubicin.
1983
1983
Role of the fast-exchanging calcium compartment in the early cardiotoxicity of anthracycline analogs.
1983
1983
Antitumor activity in mice of 4'-deoxydoxorubicin in comparison with doxorubicin.
Highly Cited
1977
Highly Cited
1977
Plasma pharmacokinetics of adriamycin and its metabolites in humans with normal hepatic and renal function.
A new, nondestructive, plasma extraction technique ultilizing chloroform:isopropyl alcohol (1:1) and ammonium sulfate saturation… 
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